Non-invasive, continuous measurement for intermediate metabolite and ion dynamics of skeletal muscle during muscle contraction

本研究旨在探讨节段性多频生物阻抗技术(S-BIS)用于人体骨骼肌代谢动力学研究的可能性。我们研究了利用骨骼肌细胞膜的电学特性对水分分布进行非侵入性测量的应用。在运动过程中，在组织中氧合血红蛋白降低的同时，细胞内水分迅速增加，细胞外水分减少。从多个实验的结果来看，S-比色仪有可能检测运动过程中骨骼肌代谢的动态变化。

The aim of this study is explore the possibility of using segmental multi-frequency bioelectrical impedance spectroscopy (S-BIS) to measure the dynamics of metabolism in human skeletal muscle. We examined the application of non-invasive measurement of water distribution using electrical property of cell membrane in skeletal muscle. During exercise, intra-cellular water rapidly increased and extra-cellular water decreased at the time of decreasing oxygenated hemoglobin in the tissue. From the results of several experiments, S-BIS has a possibility to detect the dynamics of metabolism in skeletal muscle during exercise.