Non-invasive, continuous measurement for intermediate metabolite and ion dynamics of skeletal muscle during muscle contraction

本研究的目的是探索利用多频生物阻抗谱（S-BIS）测量人体骨骼肌代谢动力学的可能性。我们研究了利用骨骼肌细胞膜电学特性非侵入性测量水分分布的应用。运动时，细胞内水分迅速增加，细胞外水分减少，同时组织含氧血红蛋白减少。从几个实验的结果来看，S-BIS有可能检测运动过程中骨骼肌的代谢动态。

The aim of this study is explore the possibility of using segmental multi-frequency bioelectrical impedance spectroscopy (S-BIS) to measure the dynamics of metabolism in human skeletal muscle. We examined the application of non-invasive measurement of water distribution using electrical property of cell membrane in skeletal muscle. During exercise, intra-cellular water rapidly increased and extra-cellular water decreased at the time of decreasing oxygenated hemoglobin in the tissue. From the results of several experiments, S-BIS has a possibility to detect the dynamics of metabolism in skeletal muscle during exercise.