Osmotic fragility of erythrocyte membrane caused by the change of Band 3
Osmotic fragility of erythrocyte membrane caused by the change of Band 3
Band 3变化引起的红细胞膜渗透脆性
批准号：
23650407
负责人：
KANAO Yoji
金额：
$1.08万
依托单位国家：
日本
项目类别：
Grant-in-Aid for Challenging Exploratory Research
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 2012
中文摘要
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英文摘要
The purpose of this study is to clarify the differences between fragile red cells and not fragile ones through the differences of proteins which compose those red cell. In the analysis of SDS-PAGE , thick bands are found in tough red cells in four bands such as 120 ,80 , 66 , 60 , (kDa). Under the analysis of LC-MS/MS , ankyrin is clearly found . Thus that result suggests that the red cell membrane is fragile due to loss of a part of ankyrin.
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