Time specific expressions of autonomic receptors in the larynx of mice

小鼠喉部自主神经受体的时间特异性表达

• 批准号: 23791920
• 负责人: NISHIO Takeshi
• 金额: $ 2.16万
• 依托单位: Kyoto Prefectural University of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791920/
• 关键词: 喉頭; 自律神経受容体; 概日リズム

We tried to prove the time specific expressions of the muscarinic acetylcholine receptors and adrenergic receptors in the murine larynx. We found that the muscarinic acetylcholine receptor Chrm2 and Chrm3 are expressed in the laryngeal submucosal gland, and the adrenergic receptor Adra2a is expressed in the superior cervical ganglion. However, there was no significant circadian rhythmicity among Chrm2, Chrm3, andAdra2a mRNA levels.

我们试图证明M胆碱能受体和肾上腺素能受体在小鼠喉部的时间特异性表达。我们发现乙酰胆碱受体chrm2和chrm3在喉粘膜下腺表达，肾上腺素能受体ADRA2a在颈上神经节表达。但是，在chrm2、chrm3和ada2a基因表达水平之间没有明显的昼夜节律。