Electrochemical telomerase assay for oral cancer screening

口腔癌患者逐年增加，早期发现需要建立有效的口腔癌筛查体系，端粒酶活性作为一种肿瘤标志物早已引起人们的关注。我们应用一种新的电化学端粒酶检测方法（ECTA）进行口腔癌的筛查。采用电化学发光法（ECTA）对口腔癌患者的临床标本进行端粒酶活性检测。ECTA诊断食管癌的敏感性和特异性分别为83.3%和81.8%。ECTA可能是一个很好的早期发现口腔癌的筛查系统。

Oral cancer patients have been increasing year by year and the establishment of effective oral cancer screening system is required due to early detection.Telomerase activity has drawn attention as a cancer marker since a long time back . We have applied a new method of electrochemical telomerase assay (ECTA) for screening of oral cancers. We measured the telomerase activity of the clinical samples which were collected from oral cancer patients using ECTA. The sensitivity and specificity of ECTA was 83.3% and 81.8%, respectively. ECTA could be an excellent screening system for the early detection of oral cancer.