The recovery mechanism and cell injury from orthodontic treatment with promoter of transplanted bone marrow-derived cell migration into periodontal tissues

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In this study, we aimed that the elucidation of the molecular regulation mechanism of recovery and cytotoxicity of periodontal tissue by orthodontic mechanical stress, and to clarify the development of the control method, the full particulars of the function and dynamics of bone marrow-derived cell.Using the mouse that performed the bone marrow-derived cell transplantation, and were elucidated the involvement of bone marrow-derived cell in the surrounding bone and tissue study of cell injury to receive the periodontal ligament fibroblasts in particular periodontal ligament tissue loaded with orthodontic academic ability in mouse molars. Bone marrow stem cells were shown to engraft in a thriving site remodeling mostly in periodontal tissue showed experimentally that this phenomenon is associated with the dense and cells of the nervous system.