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Relationship between intestinal microbiota and allergy development - Novel target on allergy suppression by food

Relationship between intestinal microbiota and allergy development - Novel target on allergy suppression by food
肠道菌群与过敏发生的关系——食物抑制过敏的新靶点
批准号:
23780149
负责人:
WATANABE Jun
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
The aim of this study was to clarify the relationship between intestinal microbiota and allergy development and the effect of maternal allergen intake during lactating period on immune reactions in offspring. Microbiota was changed in the intestine of DO11.10 mice, when those were sensitized by oral OVA administration. Maternal diet affected severity of allergic reactions probably via changing in the intestinal microbiota in offspring. Native antigen was observed in breast milk after the perinatal maternal exposure of oral antigen, with resulting sensitization in offspring. However, the sensitization was not enough to induce allergic reactions, and maternal allergen exposure did not affect the severity of allergic reactions after the additional sensitization.
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会议论文
授乳期の抗原摂取が仔の免疫応答に及ぼす影響の解析
哺乳期抗原摄入对子代免疫反应的影响分析
DOI: --
发表时间: 2014
期刊: 日本農芸化学会2014年度大会
影响因子: --
作者: [阿部麻里奈, 渡辺純, 後藤真生, 石川(高野)祐子]
通讯作者: 石川(高野)祐子
Establishment of comprehensive antioxidant database for various foods commonly consumed in Japan and re-evaluation of Japanese-style diet based on antioxidant capacity consumption
Construction and evaluation of language processing algorithm for analysis on Japanese natural sentences describen in medical records.
  • 批准号:
    26330337
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.08万
  • 财政年份:
    2014
  • 负责人:
    WATANABE Jun
  • 依托单位:
Analysis on decision-making process and prediction of subsequent behavior of medical care team using medical records with the basket analysis and attention profiling mark-up language
  • 批准号:
    23590629
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.0万
  • 财政年份:
    2011
  • 负责人:
    WATANABE Jun
  • 依托单位:
Development of delivery systems of functional food factors by vesiculation and modulation of transepithelial transport
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