In vivo patch-clamp recording analysis of a pruritogen-induced itching on synaptic transmission in spinal dorsal horn
In vivo patch-clamp recording analysis of a pruritogen-induced itching on synaptic transmission in spinal dorsal horn
批准号:
23790652
负责人:
UTA Daisuke
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
The mechanism for the itch transmission in the spinal dorsal horn remains unclear. The present study was designed to analyze pruritic synaptic responses evoked in spinal dorsal horn neurons of rodents by using an in vivo whole-cell patch-clamp recording technique. The present main finding is that subpopulation of spinal dorsal horn neurons are responsible for pruritic cutaneous serotonin stimulation.
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In vivo patch-clamp analysis of pruriceptive and nociceptive synaptic transmission in the adult rat spinal dorsal horn
成年大鼠脊髓背角瘙痒和伤害性突触传递的体内膜片钳分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Uta D, Gotoh Y, Andoh T, Kuraishi Y, Imoto K, Furue H]
通讯作者:
Furue H
DOI:
10.1186/1744-8069-7-101
发表时间:
2011-12-22
期刊:
Molecular pain
影响因子:
3.3
作者:
[Lu J, Katano T, Uta D, Furue H, Ito S]
通讯作者:
Ito S
Excitatory effect of a pruritogen serotonin on synaptic transmission in adult rat spinal dorsal horn neurons in vivo
瘙痒原血清素对体内成年大鼠脊髓背角神经元突触传递的兴奋作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Uta D, Gotoh Y, Andoh T, Kuraishi Y, Imoto K and Furue H]
通讯作者:
Imoto K and Furue H
In vivo パッチクランプ法を用いた痛覚シナプス伝達の解析
体内膜片钳法分析疼痛突触传递
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Shirakawa, H., Kusano, A., Miyake, T., Konno, M., Nakagawa, T., Kaneko, S., 歌 大介]
通讯作者:
歌 大介
In vivo puritic synaptic responses elicited by cutaneous 5-HTapplication in the superficial spinal dorsal horn of adult rats
成年大鼠脊髓背角浅层皮肤应用 5-HT 引起的体内纯化突触反应
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Uta D, Gotoh Y, Andoh T, Kuraishi Y, Imoto K, Furue H]
通讯作者:
Furue H
共 43 条
In vivo patch-clamp analysis of itch transmission in central nerve system
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批准号:25860431
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2013
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负责人:UTA Daisuke
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依托单位:
海外基金