Function of mitochondrial SIRT5 protein and metabolic interactionbetween liver and skeletal muscle
Function of mitochondrial SIRT5 protein and metabolic interactionbetween liver and skeletal muscle
批准号:
23791026
负责人:
NAKAMURA Yasuhiko
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
我们通过双向电泳鉴定出尿酸氧化酶(UOX)是SIRT5的靶标。SIRT5 Tg小鼠肝脏中UOX乙酰化水平约为野生型小鼠的一半,UOX活性显著增加。
英文摘要
We identified urate oxidase (UOX) as a target of SIRT5 by using two-dimensional electrophoresis. Acetylation levels of UOX in liver of SIRT5 Tg mice were approximately half of those in wild-type mice, and UOX activity was significantly increased.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.febslet.2012.10.009
发表时间:
2012-11-30
期刊:
FEBS LETTERS
影响因子:
3.5
作者:
[Nakamura, Yasuhiko, Ogura, Masahito, Inagaki, Nobuya]
通讯作者:
Inagaki, Nobuya
マウス肝ミトコンドリアにおける Sirt5 による urate oxidaseの脱アセチル化と活性化
Sirt5 对小鼠肝线粒体中尿酸氧化酶的脱乙酰化和激活
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[中村 靖彦, 小倉 雅仁, 小倉 かさね, 田中 大祐, 稲垣 暢也]
通讯作者:
稲垣 暢也
DOI:
10.1042/bj20101708
发表时间:
2011-04-15
期刊:
BIOCHEMICAL JOURNAL
影响因子:
4.1
作者:
[Nishi, Yuichi, Fujimoto, Shimpei, Inagaki, Nobuya]
通讯作者:
Inagaki, Nobuya
Economic analysis of competition policies to modern firms, their organizational and market structures
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批准号:16K03665
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
-
财政年份:2016
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负责人:NAKAMURA Yasuhiko
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依托单位:
Political Economic Analysis on the Structure of the Bargaining of Wage Contracts
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批准号:25870113
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.16万
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财政年份:2013
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负责人:NAKAMURA Yasuhiko
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依托单位:
Economic Analysis of Horizontal Mergers in an International Oligopolisitic Market
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批准号:23730226
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$0.75万
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财政年份:2011
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负责人:NAKAMURA Yasuhiko
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依托单位:
A mode of action of divalent iron ions on the solubilization of pectin in dried soybeans
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批准号:06680027
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1994
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负责人:NAKAMURA Yasuhiko
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依托单位:
国内基金
海外基金
维生素B6调控IL-33泛素化在二型先天性淋巴細胞(ILC2)介导的呼吸道炎症反应中作用机制研究
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批准号:32000667
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项目类别:青年科学基金项目
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资助金额:24.0万元
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批准年份:2020
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负责人:张亚光
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依托单位: