Involvement of lipid-metabolizing enzymes in stress response
Involvement of lipid-metabolizing enzymes in stress response
批准号:
23659033
负责人:
ICHIJO Hidenori
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
To analyze ASK family-dependent stress signaling, we identified 55 candidate ASK activator candidates by a genome-wide RNAi screening in C. elegans. Those candidates were further analyzed in the context of neuronal differentiation, innate immunity and oxidative stress response. Finally, we identified gene X as an activator of ASK1 by comparing it with known p38signaling components.
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SOD1 as a molecular switch to initiate homeostatic ER stress response under conditions of zinc deficiency
SOD1 作为分子开关,在缺锌条件下启动内质网稳态应激反应
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Domenico Corapi, Daniel Sykes, Katsumi Inoue, Alessandra Russo, Hidenori Ichijo]
通讯作者:
Hidenori Ichijo
細胞がストレスを感じる仕組みと疾患
细胞如何感受压力和疾病
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
[20.佐藤優子, 内野哲志, 伊藤由馬, 前原一満, 大川恭行, 徳永万喜洋, 木村宏, 一條秀憲]
通讯作者:
一條秀憲
ASK family kinases in stress response and disease
ASK 家族激酶在应激反应和疾病中的作用
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Williams YN, et al., Hidenori Ichijo]
通讯作者:
Hidenori Ichijo
Stress signaling in cell death, infiammation and disease
细胞死亡、炎症和疾病中的应激信号
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kondo K, Kadowaki T, Hidenori Ichijo]
通讯作者:
Hidenori Ichijo
Ichijo, H.Stress signaling in cell death, infiammation and disease
Ichijo,H.细胞死亡、炎症和疾病中的压力信号传导
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Ichijo, H.]
通讯作者:
H.
共 22 条
Post-translational modifications of a mitochondria-resident protein and its role in systemic regulation
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A novel purification method for endogenous protein using ASKA technique
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Homeostasis Regulation via Stress Signaling and its Molecular Basis for Drug Development
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Drug development by the molecular mechanism-based analysis of stress signaling
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Regulatory mechanisms of mucosal immunity by the ASK family signals
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Regulation of cell proliferation and cell death by stress signaling in cancer
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Comprehension and application of biological information system based on the analysis of molecular mechanisms of stress response
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Analysis of the Roles for Stress-activated MAP kinases in Oral Muco-epithelium
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批准号:12470396
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资助金额:$10.3万
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依托单位:
Analysis of ASK1 and ASK2 as stress signaling intermediates.
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批准号:10470396
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Mechanisms of programd cell death and morphogenesis in cranio-facial development.
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STUDY FOR INTRACELLULAR SIGNAL TRANSDUCTION MECHANISM OF TGF-beta SUPERFAMILY.
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海外基金