Post-translational modifications of a mitochondria-resident protein and its role in systemic regulation

线粒体驻留蛋白的翻译后修饰及其在系统调节中的作用

• 批准号: 16K15115
• 负责人: ICHIJO Hidenori
• 金额: $ 2.33万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16K15115/
• 关键词: ミトコンドリア; PGAM5; 翻訳後修飾; 代謝制御; 褐色脂肪; 細胞死

项目成果

Mislocalization, aggregation formation and defect in proteolysis in ALS

• DOI: 10.3934/molsci.2016.2.246
• 发表时间: 2016-05
• 期刊: Nature Medicine
• 影响因子: 82.9
• 作者: A. Tsubota;H. Ichijo;Kengo Homma

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.

• DOI: 10.1016/j.str.2017.05.020
• 发表时间: 2017-07-05
• 期刊: Structure (London, England : 1993)
• 作者: Chaikuad A;Filippakopoulos P;Marcsisin SR;Picaud S;Schröder M;Sekine S;Ichijo H;Engen JR;Takeda K;Knapp S
• 通讯作者: Knapp S

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

• DOI: 10.1038/s41418-017-0012-4
• 发表时间: 2018-03
• 期刊: Cell death and differentiation
• 影响因子: 12.4
• 作者: Galluzzi L;Vitale I;Aaronson SA;Abrams JM;Adam D;Agostinis P;Alnemri ES;Altucci L;Amelio I;Andrews DW;Annicchiarico-Petruzzelli M;Antonov AV;Arama E;Baehrecke EH;Barlev NA;Bazan NG;Bernassola F;Bertrand MJM;Bianchi K;Blagosklonny MV;Blomgren K;Borner C;Boya P;Brenner C;Campanella M;Candi E;Carmona-Gutierrez D;Cecconi F;Chan FK;Chandel NS;Cheng EH;Chipuk JE;Cidlowski JA;Ciechanover A;Cohen GM;Conrad M;Cubillos-Ruiz JR;Czabotar PE;D'Angiolella V;Dawson TM;Dawson VL;De Laurenzi V;De Maria R;Debatin KM;DeBerardinis RJ;Deshmukh M;Di Daniele N;Di Virgilio F;Dixit VM;Dixon SJ;Duckett CS;Dynlacht BD;El-Deiry WS;Elrod JW;Fimia GM;Fulda S;García-Sáez AJ;Garg AD;Garrido C;Gavathiotis E;Golstein P;Gottlieb E;Green DR;Greene LA;Gronemeyer H;Gross A;Hajnoczky G;Hardwick JM;Harris IS;Hengartner MO;Hetz C;Ichijo H;Jäättelä M;Joseph B;Jost PJ;Juin PP;Kaiser WJ;Karin M;Kaufmann T;Kepp O;Kimchi A;Kitsis RN;Klionsky DJ;Knight RA;Kumar S;Lee SW;Lemasters JJ;Levine B;Linkermann A;Lipton SA;Lockshin RA;López-Otín C;Lowe SW;Luedde T;Lugli E;MacFarlane M;Madeo F;Malewicz M;Malorni W;Manic G;Marine JC;Martin SJ;Martinou JC;Medema JP;Mehlen P;Meier P;Melino S;Miao EA;Molkentin JD;Moll UM;Muñoz-Pinedo C;Nagata S;Nuñez G;Oberst A;Oren M;Overholtzer M;Pagano M;Panaretakis T;Pasparakis M;Penninger JM;Pereira DM;Pervaiz S;Peter ME;Piacentini M;Pinton P;Prehn JHM;Puthalakath H;Rabinovich GA;Rehm M;Rizzuto R;Rodrigues CMP;Rubinsztein DC;Rudel T;Ryan KM;Sayan E;Scorrano L;Shao F;Shi Y;Silke J;Simon HU;Sistigu A;Stockwell BR;Strasser A;Szabadkai G;Tait SWG;Tang D;Tavernarakis N;Thorburn A;Tsujimoto Y;Turk B;Vanden Berghe T;Vandenabeele P;Vander Heiden MG;Villunger A;Virgin HW;Vousden KH;Vucic D;Wagner EF;Walczak H;Wallach D;Wang Y;Wells JA;Wood W;Yuan J;Zakeri Z;Zhivotovsky B;Zitvogel L;Melino G;Kroemer G
• 通讯作者: Kroemer G

Mitogen-activated protein kinases as key players in osmotic stress signaling.

• DOI: 10.1016/j.bbagen.2016.05.032
• 发表时间: 2016-09
• 期刊: Biochimica et biophysica acta
• 作者: Xiangyu Zhou;I. Naguro;H. Ichijo;Kengo Watanabe

ASK family kinases in Stress Signaling and Disease

ASK 家族激酶在应激信号传导和疾病中的作用

• 发表时间: 2017
• 作者: 神谷岳洋、李保海、John Danku;David Salt, 山上睦、藤原徹;Hidenori Ichijo
• 通讯作者: Hidenori Ichijo