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Regulation of cell proliferation and cell death by stress signaling in cancer

Regulation of cell proliferation and cell death by stress signaling in cancer
癌症中应激信号对细胞增殖和细胞死亡的调节
批准号:
17014013
负责人:
ICHIJO Hidenori
金额:
$35.2万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2009

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中文摘要
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英文摘要
This study aimed at analyzing the mechanisms by which cancer cells acquire abnormal proliferation and death-resistant phenotypes in the context of perturbation of stress signaling. By using ASK family knockout mice, we found that stress-activated MAP kinases play pivotal roles in development and expansion of human cancer.
期刊论文(117)
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DOI: 10.1016/j.neures.2009.12.003
发表时间: 2010-03-01
期刊: NEUROSCIENCE RESEARCH
影响因子: 2.9
作者: [Kumakura, Karen, Nomura, Hiroshi, Matsuki, Norio]
通讯作者: Matsuki, Norio
DOI: 10.1002/jcp.20465
发表时间: 2006-02-01
期刊: JOURNAL OF CELLULAR PHYSIOLOGY
影响因子: 5.6
作者: [Mizumura, K, Takeda, K, Ichijo, H]
通讯作者: Ichijo, H
Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAP kinase pathway for extracelluler ATP-induced apoptosis in macrophage
细胞外 ATP 诱导巨噬细胞凋亡需要活性氧依赖的 ASK1-p38 MAP 激酶途径激活
DOI: --
发表时间: 2008
期刊: J. Biol. Chem 283
影响因子: --
作者: [Noguchi, T., et. al.]
通讯作者: et. al.
Serine 58 of 14-3-3{zeta} is a molecular switch regulating ASK1 and oxidant stress-induced cell death
14-3-3{zeta} 的丝氨酸 58 是调节 ASK1 和氧化应激诱导的细胞死亡的分子开关
DOI: --
发表时间: 2009
期刊: Mol.Cell.Biol. 29
影响因子: --
作者: [Zhou, J., et al.]
通讯作者: et al.
77
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    • 批准号:
      16K15115
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2016
    • 负责人:
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    • 依托单位:
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    • 批准号:
      25221302
    • 项目类别:
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    • 资助金额:
      $136.95万
    • 财政年份:
      2013
    • 负责人:
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    A novel purification method for endogenous protein using ASKA technique
    • 批准号:
      25650061
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.66万
    • 财政年份:
      2013
    • 负责人:
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    • 批准号:
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    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
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    • 财政年份:
      2011
    • 负责人:
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    • 依托单位:
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