Study on immune evasion mechanism by Staphylococcus aureus via immune inhibitory receptors
Study on immune evasion mechanism by Staphylococcus aureus via immune inhibitory receptors
批准号:
23659223
负责人:
ARASE Hisashi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Host immune response plays an important role in the regulation of bacterial infection. On the other hand, some bacteria seem to have certain immune regulatory mechanism. In the present study, we have analyzed mechanism of immune evasion via inhibitory immune receptors. We found that Staphylococcus aureus expresses a certain ligand for inhibitory PILRα, one of immune inhibitory receptors. Furthermore, we found that there are certain bacteria that express the ligand of activating receptors that have high homology to inhibitory receptors.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
ペア型レセプターPILRのリガンド認識における糖鎖修飾の機能
糖基化在配对受体 PILR 配体识别中的作用
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Maeda K, Almofty SA, Shimoda M, Singh SK, Eid MMA, Kawabata T, Ikeda T, Shida H, Koito A, Sakaguchi N., 荒瀬 尚]
通讯作者:
荒瀬 尚
Newly Identified Varicella-Zoster Virus(VZV) Entry Receptor Expressed in Hematopoietic Cells
新鉴定的水痘带状疱疹病毒(VZV)进入受体在造血细胞中表达
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Tadahiro Suenaga, Fuminori Arisawa, Yasuko Mori, Hisashi Arase]
通讯作者:
Hisashi Arase
The development of colitogenic CD4+ T cells is regulated by IL-7 in collaboration with natural killer cell function in a murine model of colitis
在小鼠结肠炎模型中,IL-7 与自然杀伤细胞功能协同调节致结肠 CD4 T 细胞的发育
DOI:
--
发表时间:
2012
期刊:
J Immunol
影响因子:
4.4
作者:
[Nagaishi T, Watanabe M(他11名)]
通讯作者:
Watanabe M(他11名)
大阪大学微生物病研究所/免疫学フロンティア研究センター 免疫化学分野
大阪大学微生物疾病研究所/免疫学前沿研究中心免疫化学系
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
水痘帯状疱疹ウイルス(VZV)の膜融合機序の解析
水痘带状疱疹病毒(VZV)膜融合机制分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[末永忠広, 松本麻紀, 森康子, 荒瀬尚]
通讯作者:
荒瀬尚
共 9 条
Mechanism of misfolded protein transportation to outside cells
-
批准号:25670143
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2013
-
负责人:ARASE Hisashi
-
依托单位:
Analysis of function of misfolded proteins presented on MHC class II molecules.
-
批准号:24659223
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2012
-
负责人:ARASE Hisashi
-
依托单位:
Mechanism of herpesvirus infection
-
批准号:23390112
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.65万
-
财政年份:2011
-
负责人:ARASE Hisashi
-
依托单位:
New immune regulatory mechanism by paired receptors
-
批准号:20390143
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.56万
-
财政年份:2008
-
负责人:ARASE Hisashi
-
依托单位:
Elucidation of novel immune regulatory mechanism by PILR that belongs to NK cell receptor family.
-
批准号:18390151
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.77万
-
财政年份:2006
-
负责人:ARASE Hisashi
-
依托单位:
Immune regulation by new NK receptor family molecules
-
批准号:16390141
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.54万
-
财政年份:2004
-
负责人:ARASE Hisashi
-
依托单位:
Mechanism of immune-surveillance and immune-regulation by paired receptors
-
批准号:16043210
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
-
资助金额:$25.34万
-
财政年份:2003
-
负责人:ARASE Hisashi
-
依托单位:
Analysis of signaling molecules for NK cell receptors
-
批准号:09670328
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:1997
-
负责人:ARASE Hisashi
-
依托单位:
海外基金