A new approach to evaluate the efficacy of the smoking cessation counseling by using brain blood flow monitoring -preliminary studies-

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We conducted two studies of hemodynamic response in the brain to evaluate objectively and scientifically the efficacy of smoking cessation counseling by pharmacists. (1) the reproducibility of brain blood flow using a NIRS by three cognitive tasks, (2) the effect of smoking and short-term smoking cessation on brain blood flow.We selected LFT for our study, because it showed the most sufficient result in reproducibility among three cognitive tasks. It was suggested that the change of brain blood flow was more significantly influenced by addiction, withdrawal symptoms, and urge at the smoking cessation than nicotine concentration in blood. It is necessary to consider the influence of addiction, withdrawal symptoms and urge, when we plan the study protocol to evaluate the efficacy of smoking cessation counseling by pharmacists.