Intervention threshold for hip geometric indices according to the risk of hip fractures in Japanese women

评价了髋关节结构分析（HSA），一种股骨近端的几何评估，是否可以用于预测日本女性在随后的15年中髋部骨折的风险。我们分析了1438名在JPOS基线研究时年龄在40岁及以上的女性，其HSA值从基线时获得的髋关节DXA图像中提取，并确定了15年随访期间髋部骨折的发生率。36名女性发生髋部骨折。股骨窄颈处的截面模量与髋部骨折风险显著相关，与年龄和估计的体积骨密度无关（调整后的风险比：1.92（95%置信区间：1.17，3.14））。HSA指数可用作髋部骨折的风险评估方法。

e evaluated whether the hip structure analysis (HSA), a geometric assessment of the proximal femur, could be used to predict hip fracture risk in subsequent 15 years in Japanese women. We analyzed 1438 women who were aged 40 years and older at the time of the JPOS baseline study, whose HSA values were extracted from their hip DXA image obtained at baseline, and whose incidence of hip fracture during the 15 years of follow-up was determined. 36 women suffered from hip fractures. The section modulus at the narrow neck of the femur was significantly associated with hip fracture risk independently of age and estimated volumetric bone density (adjusted hazard ratio: 1.92 (95% confidence interval: 1.17, 3.14)). HSA indices may be used as a risk assessment method for hip fractures.