Intervention threshold for hip geometric indices according to the risk of hip fractures in Japanese women

日本女性髋部骨折风险的髋部几何指标干预阈值

• 批准号: 23659362
• 负责人: IKI Masayuki
• 金额: $ 2.58万
• 依托单位: Kinki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659362/
• 关键词: 骨粗鬆症; 大腿骨近位部骨折; 骨構造解析; リスク評価; 成人保健; 骨折; 大腿骨近位部構造解析; 骨折リスク評価; コホート研究; 大腿骨起因部構造解析

e evaluated whether the hip structure analysis (HSA), a geometric assessment of the proximal femur, could be used to predict hip fracture risk in subsequent 15 years in Japanese women. We analyzed 1438 women who were aged 40 years and older at the time of the JPOS baseline study, whose HSA values were extracted from their hip DXA image obtained at baseline, and whose incidence of hip fracture during the 15 years of follow-up was determined. 36 women suffered from hip fractures. The section modulus at the narrow neck of the femur was significantly associated with hip fracture risk independently of age and estimated volumetric bone density (adjusted hazard ratio: 1.92 (95% confidence interval: 1.17, 3.14)). HSA indices may be used as a risk assessment method for hip fractures.

我们评估了髋结构分析（HSA），一种股骨近端几何评估，是否可以用于预测日本女性随后15年的髋部骨折风险。我们分析了1438名在JPOS基线研究时年龄在40岁及以上的女性，从基线时获得的髋部DXA图像中提取其HSA值，并确定其在15年随访期间髋部骨折的发生率。36名女性髋部骨折。股骨窄颈处的截面模量与髋部骨折风险显著相关，与年龄和估计的体积骨密度无关（校正风险比：1.92(95%可信区间：1.17,3.14)）。HSA指数可作为髋部骨折的风险评估方法。