Analysis of human fetal hematopoiesis using human ES cells
Analysis of human fetal hematopoiesis using human ES cells
批准号:
23659533
负责人:
TSUJI Kohichiro
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
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英文摘要
We established a coculture system of human ES cells with autologous stromal cells derived from human ES cells to induce their differentiation into hematopoietic/blood cells, truly reflecting human fetal hematopoiesis. The human ES cell-derived stromal cells revealed a homologous phenotype of mesenchymal stem cells(MSCs), and hematopoietic/blood cells developed in the coculture with these human ES cell-derived MSCs were shown to originate from adult-type hematopoiesis. The present culture system using autologous human ES cell. derived MSCs can be useful for the analysis of human fetal hematopoiesis.
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DOI:
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发表时间:
2010
期刊:
影响因子:
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作者:
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DOI:
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2011
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发表时间:
2011
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发表时间:
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共 28 条
Investigation into the molecular mechanisms for the occurrence of leukemia using iPS cells derived from congenital bone marrow failure syndrome and establishment of the methods to prevent its occurrence
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批准号:24659489
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2012
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负责人:TSUJI Kohichiro
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依托单位:
Establishment of a method inducing embryonic stem cells to differentiate to hematopoietic stem cells (HSC) for therapeutic HSC transplantation
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批准号:20390291
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
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财政年份:2008
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负责人:TSUJI Kohichiro
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依托单位:
Generation of transplantable hematopoietic stem cells based from human embryonic stem cells
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批准号:17390297
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.33万
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财政年份:2005
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负责人:TSUJI Kohichiro
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依托单位:
The induction cf the differentiation of human embryonic stem cells into hematopoietic stem and progenitor cells.
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批准号:15390321
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.47万
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财政年份:2003
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负责人:TSUJI Kohichiro
-
依托单位:
Induction of differentiation of monkey embryonic stem cells into tissue-specific functional cells
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批准号:12557067
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.13万
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财政年份:2000
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负责人:TSUJI Kohichiro
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依托单位:
Analysis of the molecular mechanism regulating the development of hematopoietic stem cells in cord blood and their application to ex vivo expansion
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批准号:10470174
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$3.46万
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财政年份:1998
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负责人:TSUJI Kohichiro
-
依托单位: