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Analysis of human fetal hematopoiesis using human ES cells

Analysis of human fetal hematopoiesis using human ES cells
使用人类 ES 细胞分析人类胎儿造血功能
批准号:
23659533
负责人:
TSUJI Kohichiro
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 --

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项目成果

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中文摘要
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英文摘要
We established a coculture system of human ES cells with autologous stromal cells derived from human ES cells to induce their differentiation into hematopoietic/blood cells, truly reflecting human fetal hematopoiesis. The human ES cell-derived stromal cells revealed a homologous phenotype of mesenchymal stem cells(MSCs), and hematopoietic/blood cells developed in the coculture with these human ES cell-derived MSCs were shown to originate from adult-type hematopoiesis. The present culture system using autologous human ES cell. derived MSCs can be useful for the analysis of human fetal hematopoiesis.
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影响因子: --
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28
    Investigation into the molecular mechanisms for the occurrence of leukemia using iPS cells derived from congenital bone marrow failure syndrome and establishment of the methods to prevent its occurrence
    • 批准号:
      24659489
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2012
    • 负责人:
      TSUJI Kohichiro
    • 依托单位:
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    • 批准号:
      20390291
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.9万
    • 财政年份:
      2008
    • 负责人:
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    • 依托单位:
    Generation of transplantable hematopoietic stem cells based from human embryonic stem cells
    • 批准号:
      17390297
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.33万
    • 财政年份:
      2005
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    • 依托单位:
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    • 批准号:
      15390321
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      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
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      2003
    • 负责人:
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    • 依托单位: