Large-scale screening system of low molecular compounds forrealization of regenerative medicine for liver diseases
Large-scale screening system of low molecular compounds forrealization of regenerative medicine for liver diseases
批准号:
23659650
负责人:
SHIOTA Goshi
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
In order to pick up low molecular compounds which stimulate hepatic differentiate of human mesenchymal stem cells, we have developed a cell-based screening system using the #7-1-2 cells, which have TCF motif and have high luciferase activity in a dose-dependent manner, constantly and stably respond to Wnt/beta-catenin signals.
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会议论文
Enhancing effect of retinoids on anti-cancerous drugs by regulating intracellular molecules
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批准号:25670368
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2013
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负责人:SHIOTA Goshi
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依托单位:
レチノイン酸応答性の新規機能性RNAの同定による肝細胞癌の診療への応用
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批准号:20390209
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
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财政年份:2008
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负责人:SHIOTA Goshi
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依托单位:
Development of expanding and differentiation-promoting system ex vivo for liver regeneration
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批准号:16390209
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.15万
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财政年份:2004
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负责人:SHIOTA Goshi
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依托单位:
Development of method of transdifferentiation of human umbilical cord blood cells to hepatocyte
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批准号:14570469
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2002
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负责人:SHIOTA Goshi
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依托单位:
Functional analysis of retinoic acid receptor in liver
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批准号:10670473
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:1998
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负责人:SHIOTA Goshi
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依托单位:
Analysis of anti-tumor effect of HGF in transgenic mice
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批准号:07807057
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:SHIOTA Goshi
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依托单位:
海外基金