Development of new central neuropathic pain model

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Neuropathic pain is defined as pain arising as a direct consequence of a lesion or diseaseaffecting the somatosensory system. There are two types of neuropathic pain, such asperipheral neuropathic pain and central neuropathic pain. Neuropathic pain is known tobe refractory to drug therapy . Especially , central neuropathic pain is an intractable pain. We have no clinically relevant animal central neuropathic pain model and this is why newefficacious therapy was not developed. In this project, I intended to develop new centralneuropathic pain model. I injected blood to various brain regions, such as thalamus. Unfortunately , I could not find any sings of central pain which mimic clinical centralneuropathic pain