in vitro artificial extracellular microenvironments to investigate the mechanisms of cell regulations

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Cells in a body or tissues are placed in cellular microenvironments, and regulated their functions as well as fate decision in a highly regulated manner. In this study, I tried to create artificial cellular microenvironments with microfluidic and nanotechnologies to establish a new regulatory system for human pluripotent stem cells (hPSCs). The obtained results and findings will contribute the advancement of regenerative medicine and drug development using hPSCs.