Analysis on proteins and its function of porcine milk. Aiming the establishment of healthy early weaning system

研究成果总结如下；1. 2.猪乳蛋白的特性；2 .母猪初乳前后泌乳分泌量和免疫球蛋白A、G浓度的评价；3 .分娩后24 h猪初乳细胞群及淋巴细胞占总细胞百分比的变化。猪初侧T细胞与血液T细胞特征基因表达的比较，4。出生后24小时初乳摄取量对仔猪免疫功能尤其是体液免疫功能的影响6. 猪回肠基因表达谱的发育变化分析。本研究揭示了猪初乳蛋白和细胞的种类和功能。此外，本研究表明，初乳的摄入影响了仔猪体液免疫的发育，并且回肠基因表达谱在发育的某个时期发生了剧烈的变化。

The summary of the research achievements are; 1. Characterization of porcine milk proteins, 2. Evaluation of secretion volume and immunoglobulin A and G concentrations in sow colostrum from anterior to posterior teats, 3. Analysis of cell population in porcine colostrum, and change in lymphocyte percentage in total cells during 24 hrs after parturition, 4. Identification of characteristic genes expressed in porcine colostral T cell in comparison to blood T cell, 5. Effect of colostrum intake during first 24 hrs of life on the development of immunity, especially on humoral immunity, in piglets. 6. Analysis on developmental change in gene expression profile in porcine ileum. This research revealed variety and function of porcine colostral protein and cells. Additionally, this research suggested that colostrum intake affect the development of humoral immunity in piglet and that gene expression profile in ileum drastically changes at a certain period of the development.