Establishment of molecular basis for improving the treatment efficacy of chronic hepatitis C and preventing the occurrence of hepatocellular carcinoma.

为提高慢性丙型肝炎治疗效果、预防肝细胞癌的发生奠定分子基础。

• 批准号: 24390187
• 负责人: HONDA Masao
• 金额: $ 11.4万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24390187/
• 关键词: 肝炎; 肝癌; 自然免疫; C型肝炎ウイルス; 肝浸潤リンパ球; IL28B; 治療抵抗性; C型肝炎; 肝細胞癌

项目成果

New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia.

• DOI: 10.1371/journal.pone.0086449
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Nishida N;Sawai H;Kashiwase K;Minami M;Sugiyama M;Seto WK;Yuen MF;Posuwan N;Poovorawan Y;Ahn SH;Han KH;Matsuura K;Tanaka Y;Kurosaki M;Asahina Y;Izumi N;Kang JH;Hige S;Ide T;Yamamoto K;Sakaida I;Murawaki Y;Itoh Y;Tamori A;Orito E;Hiasa Y;Honda M;Kaneko S;Mita E;Suzuki K;Hino K;Tanaka E;Mochida S;Watanabe M;Eguchi Y;Masaki N;Murata K;Korenaga M;Mawatari Y;Ohashi J;Kawashima M;Tokunaga K;Mizokami M
• 通讯作者: Mizokami M

非環式レチノイド投与に伴う肝組織遺伝子発現変化と肝線維化・発癌抑制機構

与非环类维生素A给药相关的肝组织基因表达的变化以及抑制肝纤维化和癌发生的机制

• 发表时间: 2012
• 作者: Hamaguchi S.;et al;本多 政夫
• 通讯作者: 本多 政夫

Heterogeneous nuclear ribonucleoprotein A2/B1 in association with hTERT is a potential biomarker for hepatocellular carcinoma

• DOI: 10.1111/j.1478-3231.2012.02778.x
• 发表时间: 2012-08-01
• 期刊: LIVER INTERNATIONAL
• 影响因子: 6.7
• 作者: Mizuno, Hideki;Honda, Masao;Kaneko, Shuichi
• 通讯作者: Kaneko, Shuichi

Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma.

• DOI: 10.1002/hep.27093
• 发表时间: 2014-11
• 期刊: HEPATOLOGY
• 影响因子: 13.5
• 作者: Yamashita, Taro;Kitao, Azusa;Matsui, Osamu;Hayashi, Takehiro;Nio, Kouki;Kondo, Mitsumasa;Ohno, Naoki;Miyati, Tosiaki;Okada, Hikari;Yamashita, Tatsuya;Mizukoshi, Eishiro;Honda, Masao;Nakanuma, Yasuni;Takamura, Hiroyuki;Ohta, Tetsuo;Nakamoto, Yasunari;Yamamoto, Masakazu;Takayama, Tadatoshi;Arii, Shigeki;Wang, XinWei;Kaneko, Shuichi
• 通讯作者: Kaneko, Shuichi

No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.

• DOI: 10.1186/1471-2350-13-47
• 发表时间: 2012-06-19
• 期刊: BMC medical genetics
• 作者: Sawai H;Nishida N;Mbarek H;Matsuda K;Mawatari Y;Yamaoka M;Hige S;Kang JH;Abe K;Mochida S;Watanabe M;Kurosaki M;Asahina Y;Izumi N;Honda M;Kaneko S;Tanaka E;Matsuura K;Itoh Y;Mita E;Korenaga M;Hino K;Murawaki Y;Hiasa Y;Ide T;Ito K;Sugiyama M;Ahn SH;Han KH;Park JY;Yuen MF;Nakamura Y;Tanaka Y;Mizokami M;Tokunaga K
• 通讯作者: Tokunaga K