Elucidation of the mechanisms of HBV infection using single cell transcriptome analysis

利用单细胞转录组分析阐明 HBV 感染机制

• 批准号: 16K15426
• 负责人: HONDA Masao
• 金额: $ 2.16万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16K15426/
• 关键词: ウイルス; 遺伝子; 感染症; 発現制御; ウィルス

项目成果

Efficient Suppression of Hepatitis C Virus Replication by Combination Treatment with miR-122 Antagonism and Direct-acting Antivirals in Cell Culture Systems.

• DOI: 10.1038/srep30939
• 发表时间: 2016-08-03
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Liu F;Shimakami T;Murai K;Shirasaki T;Funaki M;Honda M;Murakami S;Yi M;Tang H;Kaneko S
• 通讯作者: Kaneko S

Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma.

• DOI: 10.1186/s12885-016-2380-4
• 发表时间: 2016-05-31
• 期刊: BMC cancer
• 影响因子: 3.8
• 作者: Terashima T;Yamashita T;Horii R;Arai K;Kawaguchi K;Kitamura K;Yamashita T;Sakai Y;Mizukoshi E;Honda M;Kaneko S
• 通讯作者: Kaneko S

Altered gene expression in T-cell receptor signalling in peripheral blood leucocytes in acute coronary syndrome predicts secondary coronary events.

• DOI: 10.1136/openhrt-2016-000400
• 发表时间: 2016
• 期刊: Open heart
• 影响因子: 2.7
• 作者: Takashima S;Usui S;Kurokawa K;Kitano T;Kato T;Murai H;Furusho H;Oda H;Maruyama M;Nagata Y;Usuda K;Kubota K;Takeshita Y;Sakai Y;Honda M;Kaneko S;Takamura M
• 通讯作者: Takamura M

Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model.

• DOI: 10.18632/oncotarget.15304
• 发表时间: 2017-03-14
• 期刊: Oncotarget
• 作者: Takegoshi K;Honda M;Okada H;Takabatake R;Matsuzawa-Nagata N;Campbell JS;Nishikawa M;Shimakami T;Shirasaki T;Sakai Y;Yamashita T;Takamura T;Tanaka T;Kaneko S
• 通讯作者: Kaneko S

C型肝細胞癌根治治療後の肝炎ウイルス治療の 意義と宿主因子

丙型肝细胞癌根治后肝炎病毒治疗的意义及宿主因素

• 发表时间: 2016
• 作者: 本多政夫;方堂祐治;金子周一
• 通讯作者: 金子周一