Coordination of the French/German collaborative research group "Complex Fluids: From 3 to 2 Dimensions"

应针对层状系统研究磷脂与生物来源的聚电解质和糖苷聚合物的相互作用。对于涉及单层中脂质排列的两亲物单层结构研究，通过 X 射线衍射和 FTIR 光谱进行研究。聚合物排列应通过椭圆光度法、X 射线和中子反射率进行研究。偶联应通过 FTIR 和 NMR 光谱与囊泡和涂层胶体进行研究。将通过光漂白后的荧光恢复来研究脂质的横向扩散。核磁共振技术也将用于研究薄膜的膨胀和薄膜中水的比例以及薄膜和脂质头基之间的比例。特别令人感兴趣的是耦合和动力学之间的关系、聚电解质和糖苷聚合物的 so1/gel 转变及其对调节或配体结合的重要性。总而言之，该项目旨在了解耦合脂质/聚合物系统中的结构和动力学之间的关系及其与生物物理学和化学的相关性。

The interaction of phospholipids with polyelectrolytes and glycosidic polymers, both of biological origin, shall be investigated for layered systems. For amphiphile monolayers structural studies which concern the lipid arrangement in monolayers is studied by X-ray diffraction and FTIR spectroscopy. The polymer arrangement shall be investigated by ellipsometry, X-ray and Neutron reflectivity. The coupling shall be studied by FTIR and NMR spectroscopy with vesicles and coated colloids. Lateral diffusion of lipids will be investigated by fluorescence recovery after photobleaching. NMR techniques will also be employed to investigate the swelling of films and the fraction of water in the film as well a between film and lipid head groups. Of special interest will be the relation between coupling and dynamics, so1/gel transitions of polyelectrolytes and glycosidic polymers and their importance for modulation or ligand binding. Altogether the project aims at understanding the relation between structure and dynamics in coupled lipid/polymer systems and its relevance for biophysics and -chemistry.