Analysis of genetic mechanism for reduced nociceptive response by genome-wide gene expression assay

通过全基因组基因表达测定分析减少伤害性反应的遗传机制

• 批准号: 24590741
• 负责人: KASAI Shinya
• 金额: $ 3.41万
• 依托单位: Tokyo Metropolitan Institute of Medical Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24590741/
• 关键词: 疼痛感受性; 鎮痛薬感受性; 全ゲノム遺伝子発現; モデルマウス

项目成果

Factors that affect intravenous patient-controlled analgesia for postoperative pain following orthognathic surgery for mandibular prognathism.

• DOI: 10.1371/journal.pone.0098548
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Aoki Y;Yoshida K;Nishizawa D;Kasai S;Ichinohe T;Ikeda K;Fukuda K
• 通讯作者: Fukuda K

Genome-wide association study of sensory disturbances in the inferior alveolar nerve after bilateral sagittal split ramus osteotomy.

• DOI: 10.1186/1744-8069-9-34
• 发表时间: 2013-07-08
• 期刊: Molecular pain
• 影响因子: 3.3
• 作者: Kobayashi D;Nishizawa D;Takasaki Y;Kasai S;Kakizawa T;Ikeda K;Fukuda K
• 通讯作者: Fukuda K

The association between beta-adrenergic receptor gene polymorphisms and personality traits.

β-肾上腺素能受体基因多态性与人格特质之间的关联。

• 发表时间: 2012
• 期刊: Nihon Shinkei Seishin Yakurigaku Zasshi
• 作者: Numajiri M;Aoki J;Nishizawa D;Kasai S;Ogai Y;Ikeda K;Iwahashi K
• 通讯作者: Iwahashi K

Association between genetic polymorphisms in Ca(v)2.3 (R-type) Ca2+ channels and fentanyl sensitivity in patients undergoing painful cosmetic surgery.

• DOI: 10.1371/journal.pone.0070694
• 发表时间: 2013
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Ide S;Nishizawa D;Fukuda K;Kasai S;Hasegawa J;Hayashida M;Minami M;Ikeda K
• 通讯作者: Ikeda K

Genome-wide association study identified susceptibility loci associated with nicotine dependence in a Japanese population.

全基因组关联研究确定了日本人群中与尼古丁依赖相关的易感性位点。

• 作者: Takizawa D;Oshiro Y;Okumura T;Mizumoto M;Fukushima T;Ishikawa H;Tsuboi K;Kaneko M;Sakurai H;Nishizawa D
• 通讯作者: Nishizawa D