Single-Chain Folding Polymers: Creation of Precision Nanospaces and Innovative Functions

这项工作涉及通过活性自由基聚合来设计自折叠聚合物，以创建用于独特功能的精确纳米空间。 具有精确一级结构的两亲性功能无规共聚物在溶剂（水、氯仿、氟化溶剂）中通过分子内非共价（疏水、氟、氢键）相互作用有效地自折叠，在其自折叠共聚物内形成精确的纳米空间。 本论文主要完成了以下几个方面的工作：1）确定了自折叠聚合物的设计范围; 2）表征了自折叠聚合物及其内部空间/空腔; 3）自折叠聚合物的稳定化和功能化; 4）构建了精密纳米空腔（通过分子印迹）和独特的隔室（通过星星聚合物的自折叠）; 5）功能的产生（分子识别、催化）。

This work deals with the design of self-folding polymers via living radical polymerization to create precision nanospaces for unique functions. Amphiphilic functional random copolymers with precision primary structure were efficiently self-folded in solvents (water, chloroform, fluorinated solvent) with intramolecular non-covalent (hydrophobic, fluorous, hydrogen-bonding) interaction to form precision nanospaces within their self-folding copolymers. Importantly, the following points were achieved: 1) establishment of design scope of self-folding polymers; 2) characterization of self-folding polymers and resulting inner spaces/cavities; 3) stabilization and functionalization of self-folding polymers; 4) construction of precision nano cavities (by molecular imprinting) and unique compartments (by the self-folding of star polymers); 5) creation of functions (molecular recognition, catalysis).