Analysis of the regulatory network of gene expression via environmental stress-responsive alternative splicing

为了揭示植物特有的环境胁迫应答选择性剪接的基因表达调控网络，分析了atSR45a和atSR30调控剪接机制的分子机制，拟南芥中富含丝氨酸/精氨酸(SR)的蛋白质，atSR45a和atSR30调控选择性剪接效率的转录因子的生理作用，以及调节胁迫应答选择性剪接效率的新因子的功能分析。

To reveal the plant-specific regulatory network of gene expression via environmental stress-responsive alternative splicing, it was analyzed that molecular mechanisms of splicing machinery regulated by atSR45a and atSR30, the serine/arginine-rich (SR) proteins in Arabidopsis, physiological roles of transcription factors whose alternative splicing efficiencies were regulated by atSR45a and atSR30, and functional analysis of novel factors for the regulation of alternative splicing efficiency in response to stresses.