To provide a biomarker for predicting the therapeutic effect of chemotherapy to lung cancer harboring EGFR mutation.

为预测EGFR突变肺癌化疗疗效提供生物标志物。

• 批准号: 24701037
• 负责人: KANEDA Hiroyasu
• 金额: $ 2.91万
• 依托单位: Kinki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24701037/
• 关键词: 化学療法; 抗がん剤耐性; EMT; ＥＭＴ

项目成果

Multiplex genomic profiling of non-small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study.

• DOI: 10.18632/oncotarget.1906
• 发表时间: 2014-04-30
• 期刊: Oncotarget
• 作者: Okamoto I;Sakai K;Morita S;Yoshioka H;Kaneda H;Takeda K;Hirashima T;Kogure Y;Kimura T;Takahashi T;Atagi S;Seto T;Sawa T;Yamamoto M;Satouchi M;Okuno M;Nagase S;Takayama K;Tomii K;Maeda T;Oizumi S;Fujii S;Akashi Y;Nishino K;Ebi N;Nakagawa K;Nakanishi Y;Nishio K
• 通讯作者: Nishio K

SRPX2 is a novel chondroitin sulfate proteoglycan that is overexpressed in gastrointestinal cancer.

• DOI: 10.1371/journal.pone.0027922
• 发表时间: 2012
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Tanaka K;Arao T;Tamura D;Aomatsu K;Furuta K;Matsumoto K;Kaneda H;Kudo K;Fujita Y;Kimura H;Yanagihara K;Yamada Y;Okamoto I;Nakagawa K;Nishio K
• 通讯作者: Nishio K

Reversible posterior leukoencephalopathy syndrome and trastuzumab

• DOI: 10.1007/s10637-011-9696-3
• 发表时间: 2012-08-01
• 期刊: INVESTIGATIONAL NEW DRUGS
• 影响因子: 3.4
• 作者: Kaneda, Hiroyasu;Okamoto, Isamu;Nakagawa, Kazuhiko
• 通讯作者: Nakagawa, Kazuhiko

Second-line chemotherapy with S-1 after cisplatin and gemcitabine failure in patients with advance biliary tract cancer.

晚期胆道癌患者顺铂和吉西他滨失败后使用 S-1 进行二线化疗。

• 作者: Ueda S;Kawakami H;Okamoto W, Nishina S;Kudo T;Makimura C;Kiyota H;Tanaka K;Kaneda H;Fujisaka Y;Miyazaki M;Tsurutani J;Okamoto I;Kurata T;and Nakagawa K.
• 通讯作者: and Nakagawa K.

Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK-Positive Non-Small Cell Lung Cancer

• DOI: 10.1158/1078-0432.ccr-12-0392
• 发表时间: 2012-11-15
• 期刊: CLINICAL CANCER RESEARCH
• 影响因子: 11.5
• 作者: Tanizaki, Junko;Okamoto, Isamu;Nakagawa, Kazuhiko
• 通讯作者: Nakagawa, Kazuhiko