Gen-Umwelt-Interaktion beim Aufmerksamkeitsdefizit-/Hyperaktivitätssyndrom (ADHS)

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Attention deficit and hyperactivity disorder (ADHD) ist a complex childhood syndrome characterized by inattention, hyperactivity, and impulsivity. A growing body of evidence points to the interplay between genetic vulnerability and psychosocial circumstances in early life (prenatal/postnatal) being involved in pathogenesis of ADHD. Research will take place within a framework of a multicenter collaboration study conducted by three clinical units of child psychiatry (Universities of Trier, Homburg/Saar, and Wuerzburg), and a planned DFG-Research Group organized by the University of Trier that fucuses on stress-impaired pre- and postnatal development. We would like to establish a DNA and data collection from a large sample of parentoffspring trios and/or affected sib pairs with ADHD to conduct genetic, psychosocial, and behavioral studies, and to define the role of gene-environment interactions in ADHD.