Sequestration of veterinary medicines in soils

土壤中兽药的封存

• 批准号: 5446202
• 负责人: Professor Dr. Wulf Amelung
• 金额: --
• 依托单位: Arbeitsgruppe Bodenkunde und Bodenökologie
• 依托单位国家: 德国
• 项目类别: Research Units
• 财政年份: 2005
• 资助国家: 德国
• 起止时间: 2004-12-31 至 2011-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5446202?language=en
• 关键词: Sequestration; veterinary; medicines; soils

The results of the first phase suggested that there is a residual fraction which controls the sequestration and thus the fate of SDZ and its OH metabolite in soil in the long-term run (>7 months). It has been hypothesized that this sequestration is controlled by diffusion and should thus be reversible, whereas N-Ac SDZ is not sequestered in significant amount due to its fast degradation and blocking of the amino group. Up to now, all experiments have been performed using homogenized soil in the absence of plants. The objectives of this second phase are therefore (i) to elucidate the sorption and sequestration of the individual SDZ metabolites as required by the central model, (ii) to evaluate the sorption/sequestration mechanisms responsible for the formation of a residual fraction in soil, (iii) to test the hypothesis that SDZ and its OH-metabolite may be re-mobilized from this residual fraction and thus induce effects in soil in the long-term, and (iv) to elucidate the role of the rhizosphere and field conditions for the sequestration dynamics of both SDZ and DIF in the central mesocosm and field experiments.

第一阶段的结果表明，有一个残留部分，控制隔离，从而在长期运行（>7个月）的SDZ及其OH代谢物在土壤中的命运。据推测，这种螯合作用是由扩散控制的，因此应该是可逆的，而N-Ac SDZ由于其快速降解和封闭氨基而没有被大量螯合。到目前为止，所有的实验都是在没有植物的情况下使用均质化土壤进行的。因此，第二阶段的目标是（i）阐明中心模型所要求的单个SDZ代谢物的吸附和螯合，（ii）评估土壤中残留部分形成的吸附/螯合机制，（iii）检验SDZ及其OH代谢物可能从该残留部分中重新动员并从而在长期内对土壤产生影响的假设术语，和（iv）阐明的作用，根际和现场条件的隔离动态SDZ和DIF在中央围隔和现场实验。

项目成果

Analysis of aged sulfadiazine residues in soils using microwave extraction and liquid chromatography tandem mass spectrometry

• DOI: 10.1007/s00216-008-2081-1
• 发表时间: 2008-06-01
• 期刊: ANALYTICAL AND BIOANALYTICAL CHEMISTRY
• 影响因子: 4.3
• 作者: Foerster, M.;Laabs, V.;Amelung, W.
• 通讯作者: Amelung, W.

Dissipation and sequestration of the veterinary antibiotic sulfadiazine and its metabolites under field conditions.

• DOI: 10.1021/es200326t
• 发表时间: 2011-05
• 期刊: Environmental science & technology
• 影响因子: 11.4
• 作者: Ingrid Rosendahl;J. Siemens;J. Groeneweg;Elisabeth Linzbach;V. Laabs;C. Herrmann;H. Vereecken;W. Amelung