A study for intercellular signals and their control mechanisms involved in tissue remodeling in injured retina

损伤视网膜组织重塑中细胞间信号及其控制机制的研究

• 批准号: 17K11485
• 负责人: Fukushima Mikiko
• 金额: $ 3万
• 依托单位: Kumamoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K11485/
• 关键词: 眼発生・再生医学; 眼科; 再生医学; 細胞・組織; 眼科学; 再生医療

项目成果

Decreased MCP-1/CCR2 axis-mediated chemotactic effect of conjunctival fibroblasts after transdifferentiation into myofibroblasts.

结膜成纤维细胞转分化为肌成纤维细胞后，MCP-1/CCR2 轴介导的趋化作用降低。

• DOI: 10.1016/j.exer.2018.02.008
• 发表时间: 2018
• 期刊: Exp Eye Res.
• 作者: Tsutsumi-Kuroda U;Inoue T;Futakuchi A;Shobayashi K;Takahashi E;Kojima S;Inoue-Mochita M;Fujimoto T;Tanihara H.
• 通讯作者: Tanihara H.

DNA methyltransferase inhibitor suppresses fibrogenetic changes in human conjunctival fibroblasts

• 发表时间: 2019-07
• 期刊: Molecular Vision
• 影响因子: 2.2
• 作者: Hitomi Yonemura;Akiko Futakuchi;Miyuki Inoue-Mochita;Tomokazu Fujimoto;Eri Takahashi;H. Tanihara;Toshihiro Inoue

Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells

• DOI: 10.1016/j.exer.2018.02.019
• 发表时间: 2018-05-01
• 期刊: EXPERIMENTAL EYE RESEARCH
• 影响因子: 3.4
• 作者: Nakashima, Kei-Ichi;Iwao, Keiichiro;Tanihara, Hidenobu
• 通讯作者: Tanihara, Hidenobu