Quantifying the transmission dynamics of norovirus infection usning household transmission data
使用家庭传播数据量化诺如病毒感染的传播动态
基本信息
- 批准号:18J00167
- 负责人:
- 金额:$ 2.58万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for JSPS Fellows
- 财政年份:2018
- 资助国家:日本
- 起止时间:2018-04-25 至 2021-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
「家庭内の年齢の異質性を加味した感染性」と「環境を介した感染性」の推定について前年度に一定の成果を得ていたため、本年度はこの2項目についてさらなる発展と進捗とを目指した.1つめの項目については,前年度に取得したノロウイルスを原因とすることの蓋然性が高い急性胃腸炎の家庭内感染データを用い,層別化された年齢グループごとの二次感染リスクの推定に加えて、感染動態を支配するパラメータである年齢層別の伝播率と感染期間とを推定した。これまでに得られている症候群ベースのデータについて、症状の持続期間を含めて症例定義を見直してデータクリーニングを施し、データ適合を実施した。得られた結果から、低年齢層が家庭内における感染動態に大きく貢献していることが再び示された。当結果については現在論文を執筆中である.後者の課題については,2004年のオランダにおける集団発生事例データを用い、環境リザーバからの伝播率を推定した結果をもとに論文原稿を作成して投稿した.現在、個体から排出されるウイルス量の動態を加味し、感染性の時系列変化を加えた修正原稿を再投稿し、査読下にある状況である。修正後の結果も大きくは変わらず、環境リザーバへのウイルスの蓄積が感染者数,感染期間,ウイルスの生存率および感染イベントの期間の影響を大きく受け、また感染動態に貢献している可能性が示された.本年度は特に「不顕性感染者の感染性」の推定に注力する予定であったが、明瞭な結果を得るには至らなかったため引き続き解析を実施する。
It is presumed that in the previous year, the results of the previous year have been improved, and that this year's two projects have won an improvement. The performance of this year's project has been improved. In the previous year, the causes of acute gastritis in the previous year were significantly higher than that in the previous year, and the causes of acute gastritis in the previous year were significantly higher than that in the previous year. In the previous year, the causes of acute gastritis in the previous year have been obtained, and the risk of infection in families with acute gastritis in the previous year has been obtained. in the previous year, the causes of acute gastritis in the previous year have been obtained. The symptoms of the syndrome were abnormal, the symptoms were persistent, the symptoms were confirmed, and the symptoms were treated with or without treatment. In the early years of the year, we have obtained the results of the test, and we will show you again in the early years of the family. When the results show that you are now in the process of running the text, you are now in the process of running the text. In 2004, the broadcast rate of environmental health events and environmental health events was presumed to be submitted to the public. At present, the original manuscripts have been submitted to the public. At present, a series of changes have been made to improve the quality of the original manuscripts, to modify the original manuscripts, to re-submit the manuscripts, and to modify the original manuscripts. After the correction, the results showed that the number of infected persons and the number of infected persons during the period of infection. The survival rate of children, the rate of survival, the rate of infection, the incidence of infection, the possibility of infection, the likelihood of infection, the probability of infection, the possibility of infection, the probability of infection, the possibility of infection.
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
集団構造と病原体の環境中への蓄積を考慮した数理モデルの開発-ノロウイルスの集団感染事例の解析―
考虑人口结构和环境中病原体积累的数学模型的开发 - 诺如病毒群体感染案例分析 -
- DOI:
- 发表时间:2020
- 期刊:
- 影响因子:0
- 作者:Belser Jessica A.;Barclay Wendy;Barr Ian;Fouchier Ron A.M.;Matsuyama Ryota;Nishiura Hiroshi;Peiris Malik;Russell Charles J.;Subbarao Kanta;Zhu Huachen;Yen Hui-Ling;松山亮太
- 通讯作者:松山亮太
ノロウイルスの集団感染事例における環境リザーバーの役割の定量化
量化环境储存库在诺如病毒爆发病例中的作用
- DOI:
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Matsuyama R;MCM de Jong;松山亮太
- 通讯作者:松山亮太
Uncertainty and sensitivity analysis of the basic reproduction number of diphtheria: a case study of a Rohingya refugee camp in Bangladesh, November-December 2017.
- DOI:10.7717/peerj.4583
- 发表时间:2018
- 期刊:
- 影响因子:2.7
- 作者:Matsuyama R;Akhmetzhanov AR;Endo A;Lee H;Yamaguchi T;Tsuzuki S;Nishiura H
- 通讯作者:Nishiura H
Modelling environmental transmission of norovirus within a hierarchical population structure: re-analysis of an outbreak during an international scout Jamboree
在分层人口结构中模拟诺如病毒的环境传播:对国际侦察大露营期间爆发的重新分析
- DOI:
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Matsuyama R;MCM de Jong
- 通讯作者:MCM de Jong
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松山 亮太其他文献
松山 亮太的其他文献
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{{ truncateString('松山 亮太', 18)}}的其他基金
Development of optimization procedures for school closure as an infectious disease control measure by quantifying its cost-effectiveness
通过量化其成本效益,制定关闭学校作为传染病控制措施的优化程序
- 批准号:
21K17250 - 财政年份:2021
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
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