Relaction ship btween occlusion function and bone mineral density of the mancibular condyle

我们进行了志愿者研究，以评估下颌髁骨矿物质密度（BMD）的年龄相关变化及其与脊柱骨密度的相关性。对210名健康志愿者（114名男性和96名女性，年龄在5至85岁之间）的髁突和脊柱（L1-3）进行了定量计算机断层扫描。另一项独立研究对73名年轻学生（39名男性和34名女性，年龄在23至25岁之间）进行了研究。下颌髁骨密度表现出与年龄相关的变化，与脊柱骨密度相似。然而，当用t评分表达时，男性和女性下颌髁骨密度的年龄相关衰减率在程度上小于脊柱骨密度。下颌髁与脊柱骨密度的相关性在女性中较高（r= 0.78, p<0.0001），而在男性中较低（r= 0.58, p<0.0001）。在年轻学生组中，性别差异更为显著；女性下颌髁与脊柱骨密度高度相关（r=0.82, p<0.0001），而男性无相关性（r=0.22）。综上所述，这些结果表明，下颌髁骨密度随着年龄的增长而下降，其方式与腰椎骨密度相似，表明其调节机制与脊柱骨密度相同。然而，除了腰椎骨密度外，其他未定义的因素可能参与维持下颌骨密度。

We conducted volunteer studies to assess age-related changes of the mandibular condyle bone mineral density (BMD) and its correlation to the spinal BMD.Quantitative computed tomography was performed on the condyles and spines (L1-3) of 210 healthy volunteers (114 men and 96 women ; aged 5 to 85 years). A separate study was performed on 73 young student subjects (39 men and 34 women, aged 23 to 25 years). The mandibular condyle BMDshowed age-related changes similar to those of the spinal BMD.However, when expressed by T-score, the age-related decrement rates of the mandibular condyle BMD in men and women were lesser in extent compared with those of the spine BMD.Correlations in BMD between the mandibular condyle and spine were high in women (r = 0.78, p<0.0001), but moderate in men (r= 0.58, p< 0.0001). Gender-related difference was more dramatic when assessed in the young student group ; the mandibular condyle and spinal BMDs were highly correlated in women (r=0.82, p<0.0001), but no correlation was found in men (r=0.22). Taken together, these results showed that the mandibular condyle BMD decreased with age in a similar fashion to the lumbar spine BMD,suggesting the same regulatory mechanisms as in the spinal BMD.However, aside from the lumbar spine BMD, additonal undefined factor (s) may be involved in maintaining the mandibular BMD.