Development of Nervous System and Modulation of the Calling Behavior by Testosterone in Japanese Quails

日本鹌鹑神经系统的发育和睾酮对叫声行为的调节

• 批准号: 09680800
• 负责人: AOKI Kiyoshi
• 金额: $ 2.43万
• 依托单位: Sophia University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09680800/
• 关键词: Japanese quail; distress call; ICo; testosterone; chick crowing; crowing; non-genomic action; テストステロン受容体タンパク質; 5α-DHT

The aim of this study is to clarify the functional mechanism of nervous system for producing distress calls in Japanese quail chicks and crowing in adult males along with the effects of testosterone on calling behaviors.1. Implantation of a small amount of testosterone directly into mesencephalon causes chicks to emit chick crowing, while the same dose of implantation into telencephalon failed. It suggests that testosterone acts on mesencephalon to induce chick crowing.2. By electrical stimulation of the ICo chicks emit distress calls and chick crowing before and after testosterone implantation respectively. This suggests that nervous system for producing calling behavior is in the ICo and testosterone modulates calling behavior as result of its activity.3. Adult males emit crowing by electrical stimulation of the ICo, suggesting that the ICo has the nervous system for producing crowing in adult males.4. Testosterone binding proteins exist on neural membrane of neurons in the ICo, suggesting that non-genomic action of testosterone modulates calling behaviors.

这项研究的目的是阐明神经系统在日本幼鸟发出求救信号和成年雄性鸣叫中的作用机制，以及睾丸激素对叫声行为的影响。将少量的睾酮直接植入中脑会导致雏鸡发出鸣叫，而同样剂量的注射到端脑则失败。提示睾酮作用于中脑可诱导雏鸡鸣叫。通过电刺激ICO，雏鸡在注射睾酮前后分别发出求救信号和鸣叫。这表明产生叫声行为的神经系统在ICO中，睾酮作为其活动的结果调节叫声行为。成年雄性通过电刺激ICO发出鸣叫，这表明ICO具有在成年雄性中产生鸣叫的神经系统。ICO中神经元的神经膜上存在睾酮结合蛋白，提示睾酮的非基因组作用调节了叫声行为。

项目成果

Watanabe, A.and Aoki, K.: "The role of Auditory Feedback in the Maintenance of Song in Adult Male Bengalese Finches Lonchura striata var. domestica."Zoological Science. Vol.15, No. 6. 837-841 (1998)

Watanabe, A. 和 Aoki, K.：“听觉反馈在成年雄性孟加拉雀 Lonchura striata var. Domestica 鸣叫维持中的作用。”动物学科学。

Yazaki, Y., Matsushima, T.and Aoki, K: "Testosterone modulates calling behavior in Japanese quail chicks" Zoological Science.Vol.14, No.2. 219-225 (1997)

Yazaki, Y.、Matsushima, T. 和 Aoki, K：“睾酮调节日本鹌鹑雏鸡的叫声行为”《动物学科学》，第 14 卷，第 2 期。

Yazaki, Y., Matsushima, T.and Aoki, K.: "Testosterone modulates stimulation-induced calling behavior in Japanese quails."J.Comp.Physiol.A.. vol.184. 13-19 (1999)

Yazaki, Y.、Matsushima, T. 和 Aoki, K.：“睾酮调节日本鹌鹑刺激诱导的叫声行为。”J.Comp.Physiol.A.. vol.184。

Kiyoshi AOKI: "Stimulation elicits the chick crowing with testosterone in Japanese quail chicks"Zoological Science. 14. 227-231 (1997)

Kiyoshi AOKI：“刺激会引起日本鹌鹑雏鸡体内睾酮的啼叫”《动物学》。

青木清: "行動生物学"朝倉書店. 141 (1997)

青木清：《行为生物学》朝仓书店141（1997）。