EPIDEMIOLOGICAL STUDY ON THE HEALTH EFFECTS OF INDOOR BIOLOGICAL CONTAMINANTS

这项研究的目的是调查由于生物污染物和化学物质引起的室内空气质量与儿童哮喘和过敏症等过敏反应之间的关系。我们测量了1998年冬天和1999年夏天有过敏症和无过敏症儿童居住的房屋内的几种污染物水平。目标污染物包括尘螨变应原、真菌指数、甲醛、挥发性有机化合物等。虽然1998年非过敏性儿童之家的大部分化学污染物水平似乎高于过敏性儿童之家，但所有差异均不显著。1999年，非过敏性儿童之家的尘螨过敏原和其他生物污染物水平高于过敏性儿童之家。然而，在过敏儿童之家，六氯环己烷水平更高。提示有过敏问题的家庭应尽量排除污染源，应进行队列研究，了解室内环境对儿童健康的影响。

The objective of this study is to investigate the relationship between indoor air quality due to biological contaminants and chemicals, and children's allergies such as asthma and atopy. We measure several pollutant levels inside houses where children with and without allergies were living in the winter, 1998 and in the summer, 1999. Target pollutants were dust mite allergen, fungal index, HCHO, VOCs, et al.Although most chemical pollutant levels seem to be higher in non-allergic children's homes than in allergic children's homes in 1998, all differences were not significant. In 1999, dust mite allergen and other biological pollutant levels were higher in non-allergic children's homes than in allergic children's homes. However, HCHO levels were higher in allergic children's homes. These results suggest that the family with some allergic problem try to remove pollutant origins and we should conduct a cohort study to investigate the effect of indoor environment on children's health.