The comprehensive study of indoor environment and residents' health, considering chemical sensitivity

为了研究室内环境和污染物水平的变化，我们组成了两个队列，在北海道进行跟踪。甲醛有在夏天变得更高、在冬天变得更低的趋势。我们假设新建房屋的甲醛浓度最高，但结果并不支持这一假设，居民带入房屋的家具可能是甲醛浓度的贡献者，我们调查了化学敏感（CS）患者个人暴露水平的纵向变化，并观察了其个人暴露水平的季节/月趋势。CS相关症状的恢复与醛和挥发性有机化合物（VOCs）的浓度之间没有关系，但根据主动和被动采样的结果，一些化学物质可能是导致症状的原因。刚建成后及建成后，每个房间的甲醛浓度均低于20 ppb。VOC水平也很低。房子的室内环境对CS的化学污染是有利的。开始治疗的患者对CS房屋和室内环境相当满意。我们在伊豆也进行了类似的研究。我们试图根据采样器的几何形状（扩散面积和扩散长度）和VOCs的物理性质，根据菲克扩散定律推导出扩散采样器的采样率（SR）。SR也通过同时使用主动（泵）和扩散采样实验确定。对于大多数采样器和大多数VOCs，理论上确定的SR几乎相同的实验建立的SR。基于扩散理论的VOCs的SR的准确计算似乎是可能的，而不需要进行实验测量。

In order to study the indoor environment and the change in pollutant levels, we formed two cohorts to follow in Hokkaido. Formaldehyde has a tendency to become higher in the summer and lower in the winter. We supposed that formaldehyde levels in newly built houses are the highest, but results don't support it. The furniture which residents brought into the house might contribute to formaldehyde concentration.We investigated the longitudinal change of personal exposure levels for chemical sensitivity (CS) patients, and observed the seasonal/monthly trends in their personal exposure levels. No relationship between the recuperation of CS-related symptoms and the concentrations of aldehyde and volatile organic compounds (VOCs) was recognized ; although, based on the results from active and passive sampling, some of the chemicals may be responsible for the symptoms.A CS treatment house was built at Asahikawa in 2001. The formaldehyde concentration in each room was less than 20 ppb just after the construction and since then. VOC levels were also low. The indoor environment of the house is good for CS with regard to chemical contamination. Patients who started their treatment stay at the CS house were fairly satisfied with staying at the house and with indoor environment. We also conducted the similar study at Izu.We tried to derive the sampling rate (SR) for diffusion samplers from the geometry (diffusion area and diffusion length) of the samplers and the physical properties of VOCs based on Fick's law of diffusion. SRs were also determined experimentally using simultaneous active (pump) and diffusion sampling. For most samplers and most VOCs, the theoretically determined SRs were nearly the same as the experimentally established SRs. Accurate calculation of SRs for VOCs based on the diffusion theory seems possible without the need to perform experimental measurements.