Construction of an epigenetic epidemiology database for a population cohort

人群队列表观遗传流行病学数据库的构建

• 批准号: 25293144
• 负责人: MATSUBARA Tatsuaki
• 金额: $ 11.4万
• 依托单位: Aichi Gakuin University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25293144/
• 关键词: エピゲノム疫学; ゲノム疫学; 地域住民コホート; 生活習慣病; 糖尿病; 高血圧; 心筋梗塞; 遺伝子解析; 国民健康づくり; ゲノム; 循環器・高血圧

项目成果

Therapeutic efficacy of bone marrow-derived mononuclear cells in diabetic polyneuropathy is impaired with aging or diabetes.

• DOI: 10.1111/jdi.12272
• 发表时间: 2015-03
• 期刊: Journal of diabetes investigation
• 影响因子: 3.2
• 作者: Kondo M;Kamiya H;Himeno T;Naruse K;Nakashima E;Watarai A;Shibata T;Tosaki T;Kato J;Okawa T;Hamada Y;Isobe K;Oiso Y;Nakamura J
• 通讯作者: Nakamura J

Strategy for treatment of diabetic polyneuropathy by cell transplantation: Possible utilization of dental pulp stem cells.

通过细胞移植治疗糖尿病多发性神经病的策略：牙髓干细胞的可能利用。

• 发表时间: 2015
• 作者: Yui Yamamoto;Kohji Fukunaga and Yuji Owada;Naruse K
• 通讯作者: Naruse K

The immunomodulatory effects of dental pulp stem cells on diabetic polyneuropathy in streptozotocin-induced diabetic rats.

牙髓干细胞对链脲佐菌素诱导的糖尿病大鼠糖尿病多发性神经病的免疫调节作用。

• 发表时间: 2015
• 作者: Norifumi Shioda;Yuji Owada and Kohji Fukunaga;Nakatochi M;Kohji Fukunaga;Omi M
• 通讯作者: Omi M

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

• DOI: 10.1038/ng.3405
• 发表时间: 2015-11
• 期刊: Nature genetics
• 影响因子: 30.8
• 作者: Kato N;Loh M;Takeuchi F;Verweij N;Wang X;Zhang W;Kelly TN;Saleheen D;Lehne B;Leach IM;Drong AW;Abbott J;Wahl S;Tan ST;Scott WR;Campanella G;Chadeau-Hyam M;Afzal U;Ahluwalia TS;Bonder MJ;Chen P;Dehghan A;Edwards TL;Esko T;Go MJ;Harris SE;Hartiala J;Kasela S;Kasturiratne A;Khor CC;Kleber ME;Li H;Yu Mok Z;Nakatochi M;Sapari NS;Saxena R;Stewart AFR;Stolk L;Tabara Y;Teh AL;Wu Y;Wu JY;Zhang Y;Aits I;Da Silva Couto Alves A;Das S;Dorajoo R;Hopewell JC;Kim YK;Koivula RW;Luan J;Lyytikäinen LP;Nguyen QN;Pereira MA;Postmus I;Raitakari OT;Scannell Bryan M;Scott RA;Sorice R;Tragante V;Traglia M;White J;Yamamoto K;Zhang Y;Adair LS;Ahmed A;Akiyama K;Asif R;Aung T;Barroso I;Bjonnes A;Braun TR;Cai H;Chang LC;Chen CH;Cheng CY;Chong YS;Collins R;Courtney R;Davies G;Delgado G;Do LD;Doevendans PA;Gansevoort RT;Gao YT;Grammer TB;Grarup N;Grewal J;Gu D;Wander GS;Hartikainen AL;Hazen SL;He J;Heng CK;Hixson JE;Hofman A;Hsu C;Huang W;Husemoen LLN;Hwang JY;Ichihara S;Igase M;Isono M;Justesen JM;Katsuya T;Kibriya MG;Kim YJ;Kishimoto M;Koh WP;Kohara K;Kumari M;Kwek K;Lee NR;Lee J;Liao J;Lieb W;Liewald DCM;Matsubara T;Matsushita Y;Meitinger T;Mihailov E;Milani L;Mills R;Mononen N;Müller-Nurasyid M;Nabika T;Nakashima E;Ng HK;Nikus K;Nutile T;Ohkubo T;Ohnaka K;Parish S;Paternoster L;Peng H;Peters A;Pham ST;Pinidiyapathirage MJ;Rahman M;Rakugi H;Rolandsson O;Ann Rozario M;Ruggiero D;Sala CF;Sarju R;Shimokawa K;Snieder H;Sparsø T;Spiering W;Starr JM;Stott DJ;Stram DO;Sugiyama T;Szymczak S;Tang WHW;Tong L;Trompet S;Turjanmaa V;Ueshima H;Uitterlinden AG;Umemura S;Vaarasmaki M;van Dam RM;van Gilst WH;van Veldhuisen DJ;Viikari JS;Waldenberger M;Wang Y;Wang A;Wilson R;Wong TY;Xiang YB;Yamaguchi S;Ye X;Young RD;Young TL;Yuan JM;Zhou X;Asselbergs FW;Ciullo M;Clarke R;Deloukas P;Franke A;Franks PW;Franks S;Friedlander Y;Gross MD;Guo Z;Hansen T;Jarvelin MR;Jørgensen T;Jukema JW;Kähönen M;Kajio H;Kivimaki M;Lee JY;Lehtimäki T;Linneberg A;Miki T;Pedersen O;Samani NJ;Sørensen TIA;Takayanagi R;Toniolo D;BIOS-consortium;CARDIo GRAMplusCD;LifeLines Cohort Study;InterAct Consortium;Ahsan H;Allayee H;Chen YT;Danesh J;Deary IJ;Franco OH;Franke L;Heijman BT;Holbrook JD;Isaacs A;Kim BJ;Lin X;Liu J;März W;Metspalu A;Mohlke KL;Sanghera DK;Shu XO;van Meurs JBJ;Vithana E;Wickremasinghe AR;Wijmenga C;Wolffenbuttel BHW;Yokota M;Zheng W;Zhu D;Vineis P;Kyrtopoulos SA;Kleinjans JCS;McCarthy MI;Soong R;Gieger C;Scott J;Teo YY;He J;Elliott P;Tai ES;van der Harst P;Kooner JS;Chambers JC
• 通讯作者: Chambers JC

Transplantation of neural crest cells derived from 3D-aggregated dermal stem cells improves diabetic polyneuropathy in mice.

移植源自 3D 聚集的真皮干细胞的神经嵴细胞可改善小鼠的糖尿病性多发性神经病。

• 发表时间: 2015
• 作者: Kohji Fukunaga;Hideaki Tagashira and Norifumi Shioda;Kondo M
• 通讯作者: Kondo M