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Impact of Biological Coatings on Nanoparticle–Immune Cell Interactions

Impact of Biological Coatings on Nanoparticle–Immune Cell Interactions
生物涂层对纳米颗粒与免疫细胞相互作用的影响
批准号:
DP210103114
负责人:
Prof Frank Caruso
金额:
$47.53万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-05-03 至 2024-05-02

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中文摘要
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英文摘要
Nanomaterials exposed to biological environments such as blood or lymph fluids rapidly adsorb a layer of biomolecules on their surface, forming a biomolecular corona, and profoundly altering their properties. This project aims to resolve the influence of biomolecular coronas on nanoparticle–immune cell interactions by combining particle engineering, immunology, proteomics and bioinformatic analysis. The project expected outcomes are to generate new knowledge in nanomaterial–immune cell behaviour and design principles for nanoparticles with prospective applications in the agricultural, veterinary and biomedical sectors.
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Engineering Functional Antimicrobial Polypeptide Surfaces
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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Live Cell Super Resolution Imaging Facility
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    Prof Frank Caruso
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Macromolecular Engineering of Functional Metal–Ligand Materials
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  • 项目类别:
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  • 财政年份:
    2020
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    Prof Frank Caruso
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Advancing Nanomedicine through Particle Technology
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    nhmrc : 1135806
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    Research Fellowships
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    $59.23万
  • 财政年份:
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  • 负责人:
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海外基金