Electronic screening for illness using a rapid VOC Measuring system

使用快速 VOC 测量系统对疾病进行电子筛查

• 批准号: 10004456
• 金额: $ 12.62万
• 依托单位: ROBOSCIENTIFIC LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10004456
• 关键词: Electronic; screening; illness; using; rapid

There is a need for a rapid screening test for Covid-19 and other diseases which is rapid; very low cost; non-invasive; can be applied by unskilled operators and which does not involve the use of any consumables such as swabs or chemical reagents. Roboscientific has previously developed instruments for the early detection of diseases in animals such as poultry, dairy cattle, pigs through the use of electronic instruments containing proprietary high sensitivity sensors which measure the Volatile Organic Compounds (VOCs) given off in breath or other body odours. The "digital fingerprint" of the VOCs is compared to reference "fingerprints" taken from subjects infected with particular diseases. This technology has proven very successful in commercial trials, detecting chicken diseases several days sooner than traditional PCR testing. If this system works with animals it should work with humans. Attempts by others using breath samples, for example cancer diagnostics, have not been wholly successful because of variability of the invasive sampling technique and high moisture content. Roboscientific has potentially overcome the problems by adopting a far simpler, predictable and novel technique for the test. Every health worker; care worker; shop worker, etc. wears a face mask during work. The fabric of the mask adsorbs breath and spit residues containing VOCs. The mask is subsequently put into a small flask attached to a handheld VOC analyser. The flask is electrically heated and the released VOCs are sucked into the analyser and measured for comparison with reference "disease" fingerprints stored in memory. The whole process takes less than a minute.

需要一种对新冠肺炎和其他疾病的快速筛查测试，这种测试快速、成本低、非侵入性；可以由不熟练的操作员使用，并且不涉及使用任何消耗品，如棉签或化学试剂。Roboscitic此前曾开发出早期检测家禽、奶牛、猪等动物疾病的仪器，方法是使用包含专有高灵敏度传感器的电子仪器，这些传感器可以测量呼吸或其他体味中释放的挥发性有机化合物(VOC)。将挥发性有机化合物的“数字指纹”与从感染特定疾病的受试者身上提取的参考“指纹”进行比较。这项技术在商业试验中被证明是非常成功的，比传统的PCR检测提前了几天检测到鸡病。如果这个系统适用于动物，那么它也应该适用于人类。其他人使用呼气样本的尝试，例如癌症诊断，并没有完全成功，因为侵入性采样技术的变异性和高水分含量。Roboscitic采用了一种简单得多、可预测的和新颖的测试技术，有可能克服这些问题。每个卫生工作者、护理人员、商店工作人员等在工作时都戴口罩。口罩的面料可以吸附含有VOCs的呼气和唾液残留物。然后将口罩放入一个连接到手持VOC分析仪的小烧瓶中。烧瓶被电加热，释放出的VOCs被吸入分析仪，并进行测量，以便与存储在存储器中的参考“疾病”指纹进行比较。整个过程只需不到一分钟。