Analysis of Surface Functionalization of Biosensor for Accelerated Drug Development

生物传感器表面功能化分析以加速药物开发

• 批准号: 10024130
• 金额: $ 4.01万
• 依托单位: HEXAGONFAB LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10024130
• 关键词: Analysis; Surface; Functionalization; Biosensor; Accelerated

The goal of HexagonFab is to unlock the secrets of biomolecules and shed light on how they interact. The tools created by HexagonFab help researchers to develop the medicine of the future, to find the best ways to produce novel biomolecules and to assure that medicine is always safe and efficacious. The current systems used in drug discovery and development to analyse traditional molecules like proteins and small molecules are hitting their limits with the new generation of advanced drugs.HexagonFab has developed a novel sensor platform based on nearly a decade of research at the University of Cambridge, thereby offering a solution for drug developers. The goal of the project is to create the foundation for the development of a version of the HexagonFab Bolt sensor, which will enable its application towards new classes of molecules such as Ribonucleic acid (RNA) or peptides.RNA therapeutics represent a rapidly growing category of drugs that creates a new paradigm for personalized medicine and treatment of many diseases. Given the challenge of small molecules such as RNA to traditional analysis instrumentation, the HexagonFab Bolt could become the perfect solution to answer this industry need.

HisperonFab的目标是解开生物分子的秘密，并阐明它们如何相互作用。HubrionFab创建的工具帮助研究人员开发未来的药物，找到生产新型生物分子的最佳方法，并确保药物始终安全有效。目前用于药物发现和开发的分析传统分子（如蛋白质和小分子）的系统在新一代先进药物的开发中达到了极限。基于剑桥大学近10年的研究，HellonFab开发了一种新型传感器平台，从而为药物开发人员提供了解决方案。该项目的目标是为开发一个版本的HobionFab Bolt传感器奠定基础，这将使其能够应用于新的分子类别，如核糖核酸（RNA）或肽。RNA治疗代表了一个快速增长的药物类别，为个性化医疗和治疗许多疾病创造了新的范例。考虑到RNA等小分子对传统分析仪器的挑战，HobionFab Bolt可能成为满足这一行业需求的完美解决方案。