Optimization of Surface Functionalization of Biosensor for Accelerated Drug Development & Production

优化生物传感器的表面功能化以加速药物开发

• 批准号: 10039648
• 金额: $ 5.38万
• 依托单位: HEXAGONFAB LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10039648
• 关键词: Optimization; Surface; Functionalization; Biosensor; Accelerated

The goal of HexagonFab is to unlock the secrets of biomolecules and shed light on how they interact. The protein analysis instrument BOLT created by HexagonFab helps the pharmaceutical industry to develop the medicine of the future, to find the best practice to produce drugs and to ensure their efficacy and safety through convenient and accelerated quality control (QC). The current systems used in drug discovery and development to perform QC measurements are hitting their limits with laborious protocols and significant hands-on-time. HexagonFab has developed a novel sensor platform tailored for convenient and rapid QC measurements, based on nearly a decade of research at the University of Cambridge, thereby offering a solution for the drug development process in the pharmaceutical industry.As the novel sensor technology is crucial for HexagonFab's BOLT, the goal of the project is to optimise the sensor surface functionalization to bring BOLT to the market. The high specificity and sensitivity of the sensor combined with its unique technology will help the drug development industry significantly to accelerate their research and development processes, leading to safer and more efficacious drugs.

hexonfab的目标是解开生物分子的秘密，并阐明它们如何相互作用。由hexhexonfab创建的蛋白质分析仪器BOLT帮助制药行业开发未来的药物，找到生产药物的最佳实践，并通过方便和加速的质量控制（QC）确保其有效性和安全性。目前在药物发现和开发中用于执行QC测量的系统由于繁琐的协议和大量的手工时间而达到了极限。基于剑桥大学近十年的研究，hexonfab开发了一种新颖的传感器平台，为方便快速的QC测量量身定制，从而为制药行业的药物开发过程提供了解决方案。由于这种新型传感器技术对hexonfab的BOLT至关重要，因此该项目的目标是优化传感器表面的功能化，从而将BOLT推向市场。该传感器的高特异性和高灵敏度，结合其独特的技术，将有助于药物开发行业显著加快其研发进程，从而开发出更安全、更有效的药物。