POEm: Pulse Oximetry from the Ear-druM; a robust measurement site eliminating a racial bias

POEm:耳鼓脉搏血氧测定法;

基本信息

  • 批准号:
    10027966
  • 负责人:
  • 金额:
    $ 15.25万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Collaborative R&D
  • 财政年份:
    2022
  • 资助国家:
    英国
  • 起止时间:
    2022 至 无数据
  • 项目状态:
    已结题

项目摘要

Doctors and other healthcare staff often use finger clip probes attached gently to the tip of a person's finger to measure the amount of oxygen they have in their blood. Because oxygen is so important for all the processes in your body, when people are well their oxygen level is kept at a steady level. However, reducing oxygen levels can indicate that someone is suffering a serious illness and need immediate emergency treatment, including oxygen through a mask. Oxygen measurements have therefore become a routine measurement during many healthcare consultations and treatment is often decided according to the level of oxygen measured, including for COVID-19\. It is therefore essential that the oxygen readings are 1) easily collected, and 2) reliable. In particular, they must not give false reassurance that oxygen levels are healthy when in reality they are dangerously low.Evidence has emerged and been publicised by the UK government recently, that the widely used finger probe oxygen device (and ear lobe clips) are not accurate for people with darker skin colours. This has resulted in an underestimate of severe disease and putting Black, Asian and minority ethnic people at risk of not being treated for serious illness. Also, national guidelines on detecting sepsis rely on oxygen measurements. However, many under-5-year-olds have difficulty staying still for long enough to obtain a reliable reading, meaning there is insufficient information to determine if a child has sepsis, making the diagnosis and management more difficult.The project group has identified that everyone's eardrums are the same colour, offering a site at which oxygen levels can be reliably obtained for everyone. We are therefore developing and testing a wearable or handheld device (like an ear-thermometer, for example) that we hope to show is reliable for everyone, irrespective of skin colour. We also believe it will be easier to detect levels in the wriggling younger child, and will be able to give accurate measurements in the cold.This project is to test the concept of the Pulse Oximetry from the EardruM (POEM) device in collaboration with experts at University of West of England, Bristol, to allow us to move on for testing in a large population including patients of all ethnic groups
医生和其他医护人员经常使用手指夹探针轻轻附着在一个人的指尖来测量他们血液中的含氧量。因为氧气对你身体的所有过程都很重要,当人们健康时,他们的氧气水平保持在一个稳定的水平。然而,氧气水平降低可能表明某人患有严重疾病,需要立即紧急治疗,包括通过面罩吸氧。因此,在许多医疗咨询中,测量氧气已成为一项常规测量,通常根据测量的氧气水平决定治疗,包括COVID-19。因此,氧气读数必须1)容易收集,2)可靠。特别是,他们不能给人虚假的保证,说氧气含量是健康的,而实际上氧气含量低得很危险。英国政府最近公布的证据表明,广泛使用的手指探针氧气装置(和耳垂夹)对肤色较深的人并不准确。这导致了对严重疾病的低估,并使黑人、亚洲人和少数民族的人面临严重疾病得不到治疗的风险。此外,国家指导方针检测败血症依赖于氧测量。然而,许多5岁以下的孩子很难保持足够长的时间来获得可靠的读数,这意味着没有足够的信息来确定孩子是否患有败血症,这使得诊断和治疗变得更加困难。项目组已经确定每个人的耳膜都是相同的颜色,这为每个人提供了一个可靠的氧气水平。因此,我们正在开发和测试一种可穿戴或手持设备(比如耳朵温度计),我们希望证明它对每个人都是可靠的,无论肤色如何。我们还认为,这样更容易检测蠕动的幼儿体内的水平,并且能够在寒冷中进行准确的测量。这个项目是与布里斯托尔西英格兰大学的专家合作,测试耳鼓脉搏血氧仪(POEM)设备的概念,使我们能够在包括所有种族患者在内的大量人群中进行测试

项目成果

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其他文献

吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
  • DOI:
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    0
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LiDAR Implementations for Autonomous Vehicle Applications
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
生命分子工学・海洋生命工学研究室
生物分子工程/海洋生物技术实验室
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    0
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吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
  • DOI:
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    0
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
  • DOI:
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    0
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{{ truncateString('', 18)}}的其他基金

An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
  • 批准号:
    2901954
  • 财政年份:
    2028
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
  • 批准号:
    2896097
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
  • 批准号:
    2780268
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
  • 批准号:
    2908918
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
  • 批准号:
    2908693
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
  • 批准号:
    2908917
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
  • 批准号:
    2879438
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
  • 批准号:
    2890513
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
  • 批准号:
    2879865
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
  • 批准号:
    2876993
  • 财政年份:
    2027
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Studentship

相似海外基金

NSF/FDA SiR: Pulse Oximetry Measurement Errors Correlated with Patient Skin Pigmentation: Optical Mechanisms and Effect Multipliers
NSF/FDA SiR:与患者皮肤色素沉着相关的脉搏血氧饱和度测量误差:光学机制和效应乘数
  • 批准号:
    2229356
  • 财政年份:
    2023
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Standard Grant
Supporting health equity with bias-free pulse oximetry
通过无偏差脉搏血氧测定法支持健康公平
  • 批准号:
    10701873
  • 财政年份:
    2022
  • 资助金额:
    $ 15.25万
  • 项目类别:
Racial Disparities in Accuracy of Pulse Oximetry
脉搏血氧饱和度准确性的种族差异
  • 批准号:
    10451087
  • 财政年份:
    2022
  • 资助金额:
    $ 15.25万
  • 项目类别:
Racial Disparities in Accuracy of Pulse Oximetry
脉搏血氧饱和度准确性的种族差异
  • 批准号:
    10579316
  • 财政年份:
    2022
  • 资助金额:
    $ 15.25万
  • 项目类别:
Supporting health equity with bias-free pulse oximetry
通过无偏差脉搏血氧测定法支持健康公平
  • 批准号:
    10571419
  • 财政年份:
    2022
  • 资助金额:
    $ 15.25万
  • 项目类别:
Validation of Transabdominal Fetal Pulse Oximetry in Hypoxic Fetal Lamb Models
经腹胎儿脉搏血氧饱和度在缺氧胎儿羔羊模型中的验证
  • 批准号:
    10057202
  • 财政年份:
    2020
  • 资助金额:
    $ 15.25万
  • 项目类别:
Validation of Transabdominal Fetal Pulse Oximetry in Hypoxic Fetal Lamb Models
经腹胎儿脉搏血氧饱和度在缺氧胎儿羔羊模型中的验证
  • 批准号:
    10214652
  • 财政年份:
    2020
  • 资助金额:
    $ 15.25万
  • 项目类别:
Preparing for a hybrid trial of pulse oximetry de-implementation in stable infants with bronchiolitis
准备在患有细支气管炎的稳定婴儿中进行脉搏血氧测定法取消实施的混合试验
  • 批准号:
    9591911
  • 财政年份:
    2018
  • 资助金额:
    $ 15.25万
  • 项目类别:
Improved pulse oximetry performance using transmission optical flowmetry.
使用透射光流量计改进了脉搏血氧测定性能。
  • 批准号:
    9253973
  • 财政年份:
    2017
  • 资助金额:
    $ 15.25万
  • 项目类别:
Extending the capabilities of mobile device based pulse oximetry
扩展基于移动设备的脉搏血氧仪的功能
  • 批准号:
    476629-2014
  • 财政年份:
    2017
  • 资助金额:
    $ 15.25万
  • 项目类别:
    Collaborative Research and Development Grants
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