ASBMR Three Year Symposia

ASBMR 三年研讨会

• 批准号: 10158017
• 负责人: JANE Ann CAULEY
• 金额: $ 4万
• 依托单位: AMERICAN SOCIETY FOR BONE & MINERAL RES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2022-03-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10158017
• 关键词: Address; Affect; Aging; American; Area; Audience Research; Autophagocytosis; Basic Science; Biological; Biological Aging; Biology; Biology of Aging; Bone Diseases; Bone neoplasms; Clinical; Clinical Research; Communities; Complex; Development; Disease Progression; Epidemiology; Fracture; Functional disorder; Funding; Geroscience; Goals; Grant; Health; Immune System Diseases; International; Laboratories; Malignant Neoplasms; Medical Societies; Metabolic; Minerals; Morbidity - disease rate; Muscle; Muscle Mitochondria; Muscle function; Musculoskeletal; Musculoskeletal Diseases; Neoplasm Metastasis; Osteoporosis; Outcome; Pathway interactions; Patient Care; Patients; Prevention; Professional Organizations; Recording of previous events; Research; Research Personnel; Risk; Science; Scientific Societies; Scientist; Seeds; Skeleton; Societies; Soil; State-of-the-Art Reviews; Therapeutic Intervention; Translational Research; United States National Institutes of Health; Woman; base; bone; burden of illness; cancer site; cancer therapy; combat; disability; falls; healthspan; improved; innovation; interest; meetings; men; mortality; muscle aging; muscle physiology; neoplastic cell; new therapeutic target; osteoporosis with pathological fracture; palliative; prevent; programs; sarcopenia; satellite cell; skeletal; stem cells; success; symposium; targeted treatment; therapeutic target; tumor; tumor growth

The American Society for Bone and Mineral Research (ASBMR), the largest professional, scientific and medical society established to bring together clinical and laboratory-based scientists who are involved in the study of bone, mineral and musculoskeletal science, has had a successful history of conducting annual topical meetings funded by single year NIH R13 grants since 2002. In 2015, ASBMR received a three-year R13 to cover three pre-meeting symposia for 2016-2018.This application seeks funding for a three-year R13 grant to advance the field of musculoskeletal diseases by focusing on three specific areas of scientific research in 2019, 2010 and 2021: 1) “Muscle: The Path Forward to New Therapeutic Targets”; 2) “The Seed and Soil: Therapeutic Targets for Cancer in Bone”; 3) “Biology of the Aging Skeleton: Implications for Fracture Prevention”. These three areas cover a range of topics that collectively contribute to major clinical morbidity disability and mortality. The overall objective of this R13 is to stimulate further advances that will result in improved patient care for musculoskeletal diseases by bringing together the best researchers for each of the three symposia that will be held in conjunction with the ASBMR Annual Meetings. Each of the three symposia will review the state of the art in each topic area, exchanging ideas with attendees, and stimulating the interaction between young and established researchers. For each of the three symposia, attendees will be encouraged to attend the subsequent ASBMR Annual Meetings for additional opportunities to interact with musculoskeletal researchers. Agendas for all three years have been developed by an organizing committee with committed speakers and chairs for the first two years. The agendas include established and young investigators, women and men. Since about half of ASBMR membership is from outside the US, we also include a number of key international speakers. At the end of each meeting, a “dine-around” evening is planned to allow direct interaction between young investigators and more senior speakers at the meeting. In 2019, the symposium will appraise the emerging basic science of muscle (autophagy muscle, mitochondria, stem and satellite cells), translational research including development of potential therapeutic targets and to clinical research. In 2020, the symposium will focus on recent advances in the contributions of the bone microenvironment to the pathophysiology, prevention and treatment of cancer in bone. The 2021 symposium will bring together experts in geroscience and skeletal biology to enhance our understanding of biological aging that is being targeted by therapeutic interventions to increase health span and apply them to the aging skeleton.

美国骨与矿物质研究学会 (ASBMR)，最大的专业、科学和 成立医学会的目的是将参与该领域的临床和实验室科学家聚集在一起 研究骨骼、矿物质和肌肉骨骼科学，拥有举办年度专题的成功历史 自 2002 年以来，每年的会议均由 NIH R13 拨款资助。2015 年，ASBMR 获得了为期三年的 R13 涵盖 2016-2018 年的三场会前研讨会。本申请寻求为期三年的 R13 赠款资助 通过重点关注三个具体的科学研究领域来推进肌肉骨骼疾病领域 2019年、2010年和2021年：1）“肌肉：通往新治疗目标的道路”； 2）“种子和土壤： 骨癌的治疗目标”；3)“衰老骨骼的生物学：对骨折的影响 预防”。这三个领域涵盖了一系列共同导致主要临床发病率的主题 残疾和死亡率。 R13 的总体目标是刺激进一步的进步，从而导致 通过汇集各个领域最优秀的研究人员，改善了肌肉骨骼疾病的患者护理 将与 ASBMR 年会同时举行的三场研讨会。三个研讨会分别 将回顾每个主题领域的最新技术，与与会者交换想法，并激发 年轻研究人员和知名研究人员之间的互动。对于这三个研讨会的每一个，与会者都将 鼓励参加随后的 ASBMR 年会，以获得更多的互动机会 肌肉骨骼研究人员。所有三年的议程均由组委会制定 头两年都有坚定的演讲者和主席。议程包括成熟的和年轻的 调查员，女性和男性。由于大约一半的 ASBMR 成员来自美国以外，我们也 包括一些重要的国际演讲者。每次会议结束时，都会有一个“聚餐”之夜 计划允许年轻研究人员和会议上更资深的发言者之间进行直接互动。在 2019年，研讨会将对新兴的肌肉基础科学（自噬肌肉、线粒体、 干细胞和卫星细胞），转化研究，包括潜在治疗靶点的开发和 临床研究。 2020年，研讨会将重点关注骨科学贡献的最新进展 微环境对骨癌病理生理学、预防和治疗的影响。 2021年研讨会 将汇集老年科学和骨骼生物学领域的专家，以增强我们对生物衰老的理解 这是治疗干预措施的目标，以延长健康寿命并将其应用于老龄化 骨骼。