Combining new synthetic biology tools to boost crop CO2 capture and growth

结合新的合成生物学工具促进作物二氧化碳捕获和生长

• 批准号: DP210101757
• 负责人: Prof Spencer Whitney
• 金额: $ 39.48万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-04-05 至 2024-04-04
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210101757
• 关键词: Combining; new; synthetic; biology; tools

A solution for improving crop yield is to enhance the carbon dioxide fixation properties of the enzyme Rubisco whose inefficient activity often limits plant growth. This project makes use of new synthetic biology capabilities to artificially evolve Rubisco in the laboratory and select for new versions with improved performance. These beneficial changes will be introduced into crop Rubisco using targeted gene editing approaches and the improvements in photosynthesis, growth and yield evaluated. This information will aid complimentary biotechnological efforts seeking to supercharge photosynthesis and help deliver the second Green Revolution needed to meet the improvement required in future agriculture productivity and resource use.

提高作物产量的一个解决方案是增强Rubisco酶的二氧化碳固定性能，该酶的低效活性往往限制植物的生长。该项目利用新的合成生物学能力在实验室中人工进化Rubisco，并选择性能更好的新版本。这些有益的变化将通过有针对性的基因编辑方法引入作物Rubisco，并对光合作用、生长和产量的改善进行评估。这些信息将有助于寻求增强光合作用的免费生物技术努力，并有助于实现第二次绿色革命，以满足未来农业生产力和资源利用所需的改善。