The University of Iowa Clinical and Translational Science Award

摘要 爱荷华大学(UI)临床与翻译科学研究所(ICTS)由 董事会将实现三个目标--第一，领导大学翻译科学的发展； 第二，推动翻译科学成为一门独特的学科；第三，传播能力 在爱荷华州的翻译科学方面。这项任务使我们能够处理影响 需要制度解决方案的翻译科学，例如改变人类的监管流程 主题研究，开发信息基础设施，用于集成电子病历和其他 卫生保健数据，与社区组织建立双向关系，并振兴 训练有素的临床和翻译研究人员的管道。 爱荷华州是一个农村州，这带来了特殊的医疗保健需求和挑战。我们已经用了这些农村的 作为推动我们临床和转化性研究方法的催化剂的考虑，推动我们的团队 制定战略，让所有年龄和背景的农村人口参与进来，并创造新的方法 克服农村州的地理障碍。我们正在利用我们已有的社区实践 家庭医生、诊所、学校护士和药剂师网络。我们使用电子健康/电子学习 并将测试这些新参与方法的有效性。随着我们推动研究 “超越我们的边界”，我们已经创造了方法来捕捉实时的、真实的数据从家里到 将这些环境特定的、全面的数据与人类的表现联系起来。ICTS正在与 其他CTSA枢纽和国家CTR系统，以经验地测试不同的方法并开发 加速翻译的成熟战略的证据基础，可以更广泛地传播。尽管 距离和乡村驱使着我们的方法，我们开发的战略只是新的，可能更好 产生广泛代表性并提高患者、医疗团队和 院士们。通过我们的地方、州和国家合作伙伴关系，UI和ICTS准备将临床 并将发现迅速转化为各种临床环境中的医疗实践。

ABSTRACT The Institute for Clinical and Translational Science (ICTS) at the University of Iowa (UI) was established by the Board of Regents to realize three objectives – first, to lead the development of translational science at the UI; second, to advance translational science as a distinct academic discipline; and third, to disseminate capacities in translational science across the State of Iowa. This mandate enabled us to tackle large problems affecting translational science that required institutional solutions, such as transforming regulatory processes for human subjects research, developing an informatics infrastructure for integrating electronic medical record and other health care data, establishing bi-directional relationships with community organizations, and revitalizing the pipeline of well trained clinical and translational researchers. Iowa is a rural state, which brings special health care needs and challenges. We have used these rural considerations as a catalyst for driving our approach to clinical and translational research pushing our teams to develop strategies to engage rural populations of all ages and backgrounds and to create new approaches that overcome the geographic barriers in a rural state. We are capitalizing on our established community practice networks of family physicians, clinics, school nurses and pharmacists. We utilize e Health/ e Learning platforms in novel ways and will test the efficacy of these new methods of engagement. As we move research “Beyond Our Borders,” we have created methods to capture real-time, real-life data from the home and to correlate this environmentally specific, comprehensive data to human performance. The ICTS is engaging with other CTSA hubs and national CTR systems to empirically test different approaches and to develop the evidence base of proven strategies for accelerating translation that can be more broadly disseminated. Though distance and rurality drive our approaches, the strategies that we develop are simply new and potentially better ways to generate broad representation and improved participation by patients, healthcare teams and academicians. Through our local, state and national partnerships, UI and the ICTS are poised to move clinical and translational discovery rapidly into healthcare practice in a variety of clinical settings.