Effectiveness of a smoking cessation algorithm integrated into HIV primary care

项目总结/摘要 18-24岁的艾滋病毒感染者（PLWH）不成比例地使用烟草，其中一半 也有一些人使用某种形式的大麻。虽然18-24岁艾滋病毒携带者的确切数量 谁共同使用烟草和大麻是未知的，共同使用者的数量预计只会 由于不断变化的大麻立法以及越来越多的供应和普及， 吸食烟草和大麻产品不幸的是，这些变化有可能 对18-24岁艾滋病毒携带者的发病率有深远影响。据了解，烟草本身 对肺部健康有害，而大麻已被证明具有类似的生理 烟草对肺部健康的影响，烟草和大麻的综合影响， 特别是对于那些谁是vaping之间PLWH研究较少。此外，在 尝试戒烟的人，大麻的使用已被证明会导致 戒烟困难，甚至重新开始吸烟。决策算法的使用 帮助提供者在常规戒烟期间开具戒烟药物治疗处方的工具 临床护理是戒烟的一种有希望的策略。虽然父母的研究 一份补充报告旨在评估这一戒烟决策工具的有效性 在三个临床站点（华盛顿大学， 伯明翰的亚拉巴马，芬威社区健康中心），本补充材料的目的 建议是了解烟草-大麻共同使用如何影响PLWH的戒烟 年龄在18-24岁，随机接受决策算法工具。焦点小组和 将采用深入访谈的方式调查患者和提供者对烟草的态度 戒烟方式和大麻对戒烟的影响。此外，二次分析 将在18-24岁的PLWH中进行母研究具体目标1的研究。初级 结果将包括对算法工具的可行性和可接受性的评价， 6个月时的点流行率、戒断率和大麻使用频率的比较， 烟草和大麻共同使用者和只使用烟草者。这项研究的结果将有助于 通过提供18-24岁的PLWH的具体信息，通知算法的下一次迭代 同时使用烟草和大麻

Project Summary/Abstract People living with HIV (PLWH) aged 18-24 disproportionately use tobacco with half of those individuals also using some form of cannabis. While the exact amount of PLWH aged 18-24 who co-use tobacco and cannabis is unknown, the amount of co-users is only expected to increase due to changing cannabis legislation and increasing availability and popularity of vaping both tobacco and cannabis products. Unfortunately, these changes have the potential to have a profound impact on the morbidity of PLWH aged 18-24. Tobacco alone is known to be detrimental to lung health and while cannabis has been shown to have similar physiologic effects on lung health as tobacco, the combined effects of tobacco and cannabis and specifically for those who are vaping are less well studied among PLWH. Furthermore, among individuals who are attempting tobacco cessation, cannabis use has been shown to lead to difficulties with tobacco cessation and even tobacco re-initiation. Use of a decisional algorithm tool that aids providers in prescribing pharmacotherapy for tobacco cessation during routine clinical care is one promising strategy for tobacco cessation. While the parent study of this supplement seeks to evaluate the effectiveness of this decisional tool in tobacco cessation among PLWH engaged in care at three clinical sites (University of Washington, University of Alabama at Birmingham, Fenway Community Health Center), the purpose of this supplemental proposal is to understand how tobacco-cannabis co-use affects tobacco cessation in PLWH aged 18-24 who were randomized to receive the decisional algorithm tool. Focus groups and in-depth interviews will be used to examine patient and provider attitudes about tobacco cessation modalities and cannabis’ effects on cessation. Additionally, a secondary analysis from specific aim 1 of the parent study will be performed on PLWH aged 18-24. Primary outcomes will include an evaluation of the feasibility and acceptability of the algorithm tool and a comparison of the point prevalence abstinence and cannabis frequency at 6 months between tobacco and cannabis co-users and tobacco-only users. Findings from this study will help inform the next iteration of the algorithm by providing specific information on PLWH aged 18-24 who co-use tobacco and cannabis.