Washington National Primate Research Center

华盛顿灵长类研究中心 整个截面 项目摘要 这笔赠款要求为华盛顿国家灵长类动物中心的持续运作提供5年的资金支持 华盛顿大学研究中心。本拨款申请中描述的工作目标是 为基础广泛的研究和资源计划提供支持，为生物医学科学家提供 利用非人灵长类动物（NHP）模型进行人类健康相关和NHP研究的机会 生物问题。这一目标将通过支持科学知识资源、行政管理、 动物支持资源、设施和操作。需要翻译和临床前支持 在艾滋病相关研究、神经科学、功能基因组学、发育和 生殖生物学和国际项目（研究核心）。新的研究资源倡议将 开发新的NHP模型，并扩大相关的研究资源，包括额外的新核心 科学家要求支持与研究资源有关的研究，以提供新的创新研究 方向和NHP资源的更好的表征。WaNPRC将专注于有效，高效 获得中心的研究资源，特别强调对附属研究的支持 活动该提案还包括支持广泛的动物护理计划， 繁殖、圈养和研究活动（灵长类动物资源司）。行政支持也是 要求对中心的财务和业务进行适当管理，重点是改善 为研究活动提供高效率和有效的支持。要求对WaNPRC国内育种提供支持 菌落M.奈美丝蒂娜所有被安置在WaNPRC设施中的灵长类动物都被安置和照顾， 符合或超过NIH标准的条件，如《实验室护理和使用指南》所述。 动物，实验动物资源研究所（ILAR）的建议，和协会 实验动物管理的评估和认可，国际（AAALAC）认可标准 NHP。

WASHINGTON NATIONAL PRIMATE RESEARCH CENTER OVERALL SECTION PROJECT SUMMARY This grant requests 5 years of funding support for continuing operation of the Washington National Primate Research Center at the University of Washington. The goal of work described in this grant proposal is to provide support for a broad-based research and resources program, providing biomedical scientists the opportunity to conduct research using nonhuman primate (NHP) models for human health-related and NHP biologic issues. This goal will be attained through support for scientific intellectual resources, administration, animal support resources, facilities, and operations. Support is requested for translational and pre-clinical resource support in AIDS-related research, Neuroscience, Functional Genomics, Developmental and Reproductive Biology, and International Programs (Research Cores). New research resource initiatives will develop novel NHP models as well as expand related research resources, including additional new core scientists. Support for research resource related studies is requested to provide new, innovative research directions and better characterization of the NHP resource. The WaNPRC will focus on effective, efficient access to Center research resources, with particular emphasis placed on support for affiliate research activities. This proposal also includes support for a broad program of animal care and technical support for breeding, housing, and research activities (Division of Primate Resources). Administrative support is also requested to provide appropriate management of Center finances and operations, focusing on improved efficiency and effective support for research activities. Support is requested for WaNPRC domestic breeding colonies of M. nemestrina. All primates housed in WaNPRC facilities are housed and cared for under conditions that meet or exceed NIH standards as stated in the Guide for the Care and Use of Laboratory Animals, Institute for Laboratory Animal Resources (ILAR) recommendations, and the Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) accreditation standards for NHPs.