Washington National Primate Research Center

华盛顿国家灵长类研究中心 整体部分 项目总结 这笔赠款要求为华盛顿国家灵长类动物的继续运营提供5年的资金支持 华盛顿大学研究中心。这项拨款提案中所描述的工作目标是 为基础广泛的研究和资源计划提供支持，为生物医学科学家提供 利用与人类健康相关的非人灵长类(NHP)模型进行研究的机会 生物问题。这一目标将通过支持科学智力资源、行政管理、 动物支持资源、设施和操作。要求为转换和临床前提供支持 艾滋病相关研究、神经科学、功能基因组学、发育和 生殖生物学和国际项目(研究核心)。新的研究资源计划将 开发新的NHP模式并扩展相关研究资源，包括额外的新核心 科学家。要求支持与研究资源相关的研究，以提供新的、创新的研究 NHP资源的方向和更好的特性。WaNPRC将专注于有效、高效 获取中心研究资源，特别强调支持附属研究 活动。该提案还包括支持广泛的动物护理方案和技术支持 饲养、住房和研究活动(灵长类资源司)。行政支持也是 要求为中心的财务和运营提供适当的管理，重点是改进 为研究活动提供高效和有效的支持。请求为WaNPRC家养提供支持 新月形支原体的菌落。所有寄养在WaNPRC设施中的灵长类动物都在 符合或超过《实验室护理和使用指南》中规定的NIH标准的条件 动物，实验动物资源研究所(ILAR)建议，和 国际实验动物护理的评估和认可(AAALAC)认可标准 国家卫生保健计划。

WASHINGTON NATIONAL PRIMATE RESEARCH CENTER OVERALL SECTION PROJECT SUMMARY This grant requests 5 years of funding support for continuing operation of the Washington National Primate Research Center at the University of Washington. The goal of work described in this grant proposal is to provide support for a broad-based research and resources program, providing biomedical scientists the opportunity to conduct research using nonhuman primate (NHP) models for human health-related and NHP biologic issues. This goal will be attained through support for scientific intellectual resources, administration, animal support resources, facilities, and operations. Support is requested for translational and pre-clinical resource support in AIDS-related research, Neuroscience, Functional Genomics, Developmental and Reproductive Biology, and International Programs (Research Cores). New research resource initiatives will develop novel NHP models as well as expand related research resources, including additional new core scientists. Support for research resource related studies is requested to provide new, innovative research directions and better characterization of the NHP resource. The WaNPRC will focus on effective, efficient access to Center research resources, with particular emphasis placed on support for affiliate research activities. This proposal also includes support for a broad program of animal care and technical support for breeding, housing, and research activities (Division of Primate Resources). Administrative support is also requested to provide appropriate management of Center finances and operations, focusing on improved efficiency and effective support for research activities. Support is requested for WaNPRC domestic breeding colonies of M. nemestrina. All primates housed in WaNPRC facilities are housed and cared for under conditions that meet or exceed NIH standards as stated in the Guide for the Care and Use of Laboratory Animals, Institute for Laboratory Animal Resources (ILAR) recommendations, and the Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) accreditation standards for NHPs.