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中文摘要
翻译
技能发展核心-摘要 为了培养下一代血液科学人才,特别关注和致力于 血友病A的抑制剂,我们将招募具有不同背景的多样化的早期调查人员 我们技能发展核心(SDC)的参与者。这些学员将有特定的教育机会, 包括广泛的相关教学、研讨会和研讨会系列,已经在我们的3 校区:费城儿童医院/宾夕法尼亚大学校区, 佛罗里达和皇后大学。最重要的是,SDC的参与者将参与跨学科的科学 拟议的项目,这些项目将提供各种先进实验室技术的实践培训,但也 与多个学科的合作者一起指导团队科学的实践经验。这也将是 加强了3个地点之间的人员交流,使所有地点的SDC参与者都可以 利用所有机构的优势。由以下人员组成的技能发展领导委员会 在研究和指导成功方面有可靠记录的调查人员将提供科学和 向SDC参与者提供职业发展指导。具体指标将用于每年评估我们的 成功实现我们的目标。
英文摘要
Skills Development Core – Abstract In order to train the next generation of blood sciences, specifically interested and committed to the problem of inhibitors in hemophilia A, we will recruit diverse early-stage investigators with a variety of backgrounds to be participants in our skill development core (SDC). These trainees will have specific educational opportunities, including a broad range of relevant didactics, workshops, and seminar series, already occurring on our 3 campuses: The Children’s Hospital of Philadelphia/University of Pennsylvania campus, the University of Florida, and Queens University. Most importantly, SDC participants will partake in the interdisciplinary scientific projects proposed, which will provide hands-on training in various advanced laboratory techniques, but also practical experience conducing team science with collaborators across multiple disciplines. This will also be augmented by personnel exchanges between 3 locations such that SDC participants at all sites can take advantage of the strengths at all the institutions. A skill development leadership committee composed of investigators with proven track records in research and mentoring success will provide both scientific and career development guidance to SDC participants. Specific metrics will be used to annually assess our success of achieving our goal.
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Immune tolerance induction by AAV-FVIII gene therapy for canine hemophilia A with inhibitors
  • 批准号:
    10276571
  • 项目类别:
  • 资助金额:
    $74.62万
  • 财政年份:
    2021
  • 负责人:
    Valder R. Arruda
  • 依托单位:
Characterization of the Functional Repertoire and Ontogeny of FVIII Humoral Response Across Species: Project 1
  • 批准号:
    10406333
  • 项目类别:
  • 资助金额:
    $34.62万
  • 财政年份:
    2018
  • 负责人:
    Valder R. Arruda
  • 依托单位:
Biochemistry of Intrinsic Xase
  • 批准号:
    10439608
  • 项目类别:
  • 资助金额:
    $73.28万
  • 财政年份:
    2018
  • 负责人:
    Valder R. Arruda
  • 依托单位:
Molecular and cellular mechanisms of the FVIII immune response
  • 批准号:
    10162322
  • 项目类别:
  • 资助金额:
    $139.61万
  • 财政年份:
    2018
  • 负责人:
    Valder R. Arruda
  • 依托单位:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data