Integrated Health Sciences Facility Core

综合健康科学设施核心

• 批准号: 10162594
• 负责人: David M Reif
• 金额: $ 27.03万
• 依托单位: NORTH CAROLINA STATE UNIVERSITY RALEIGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-20 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10162594
• 关键词: Affect; Basic Science; Bioinformatics; Biological Models; Clinical; Clinical Research; Communities; Core Facility; Data; Data Science; Data Scientist; Discipline; Ensure; Environment; Environmental Exposure; Environmental Health; Environmental Impact; Epidemiologist; Epidemiology; Funding; Goals; Health; Health Sciences; Human; Human Resources; Institution; Integrative Medicine; Interdisciplinary Study; International; Libraries; Link; Mission; Modeling; Population; Population Study; Prevention; Public Health; Research; Research Personnel; Resources; Sampling; Scientist; Specialist; Structure; System; Tissues; Translating; Translational Research; Translations; community engagement; community organizations; data curation; data integration; data management; data science resource; data streams; data visualization; experimental study; health data; health science research; human study; improved; knowledge base; member; method development; public health priorities; success

ABSTRACT-INTEGRATIVE HEALTH SCIENCES FACILITY CORE: The Integrative Health Sciences Facility Core (IHSFC) of the Center for Human Health and the Environment (CHHE) is the central interface between basic scientists, data scientists, epidemiologists, clinical researchers, and public health practitioners. Its mission is to catalyze multidirectional translation of research between diverse model systems, population-based studies, and community partners to advance understanding about the effects of environmental exposures on human health and facilitate use of this information by affected communities to improve public health. The intentional disciplinary diversity of the IHSFC leaders has developed the Core into a highly effective resource for CHHE’s internationally renowned scientists who leverage diverse models for environmental health science (EHS) research, bioinformaticists who integrate data streams from across the health sciences, and epidemiologists and community engagement specialists who are substantively involved in local communities and translating CHHE research to improve public health. The IHSFC has been highly successful in its goal to establish key translational partnerships and resources and facilitate new and impactful interdisciplinary research connections and community engagement initiatives. Reflection on these successes revealed that a major factor in these connections was access to data science resources for interpreting, linking, and communicating results from basic science experiments through human studies and, ultimately, community engagement. Therefore, in the next funding cycle the previously separate data science efforts have been expanded and integrated into a new IHSFC Environmental Data Science Group (EDSG) that provides Center members clear access to significant data science capabilities. With expertise drawn from the Bioinformatics Research Center and the NC State Libraries, the EDSG component of IHSFC provides best-practices in data management, analysis, and sharing into all Center activities. Additionally, in the next funding cycle the IHSFC will revise its key personnel to accommodate the addition of the EDSG, will establish and extend key programmatic partnerships, and is creating new and enhancing existing resources at NC State and partner institutions. These activities will promote new opportunities for multidirectional translation between basic science, clinical research, and community organizations.

摘要综合健康科学设施核心： 人类健康与环境中心的综合健康科学设施核心（IHSFC） (CHHE) 是基础科学家、数据科学家、流行病学家、临床研究人员、 和公共卫生从业者。其使命是促进研究成果的多向转化 多样化的模型系统、基于人群的研究和社区合作伙伴，以增进对 环境暴露对人类健康的影响，并促进受影响者使用这些信息 社区改善公共卫生。 IHSFC 领导人有意实现学科多元化 将核心发展成为 CHHE 国际知名科学家的高效资源 利用多种模型进行环境健康科学 (EHS) 研究，生物信息学家整合数据 来自健康科学领域、流行病学家和社区参与专家，他们 实质性参与当地社区并转化 CHHE 研究以改善公共卫生。这 IHSFC 在建立关键转化合作伙伴关系和资源的目标方面取得了巨大成功， 促进新的、有影响力的跨学科研究联系和社区参与倡议。 对这些成功的反思表明，这些联系的一个主要因素是接触数据科学 用于通过人类解释、链接和交流基础科学实验结果的资源 研究以及最终的社区参与。因此，在下一个融资周期中，先前单独的 数据科学工作已得到扩展并整合到新的 IHSFC 环境数据科学小组中 (EDSG) 为中心成员提供了获得重要数据科学能力的清晰途径。凭借专业知识 IHSFC 的 EDSG 部分来自生物信息学研究中心和北卡罗来纳州立图书馆 为所有中心活动提供数据管理、分析和共享的最佳实践。此外，在 下一个资助周期，IHSFC 将修改其关键人员以适应 EDSG 的增加，将 建立并扩大关键的计划伙伴关系，并正在创建新的资源和增强现有资源 北卡罗来纳州立大学和合作机构。这些活动将为多向翻译带来新的机遇 基础科学、临床研究和社区组织之间的关系。