Cancer Research Training in Molecular Biology

摘要 弗吉尼亚大学的癌症研究培训计划（CRTP）汇集了教师和 对癌症生物学有共同兴趣的学员参加癌症研究综合计划 和发现CRTP的总体目标是培养一代癌症研究人员， 熟悉癌症研究的最新技术;对癌症基因组学有广泛的了解， 癌症的分子驱动因素;并了解肿瘤细胞的外在，微环境和免疫 这些相互作用有助于肿瘤生长和转移。此外，我们的培训计划旨在发展 学员谁是善于与基础科学家，转化研究人员，临床试验， 医生促进发现和改善癌症护理的结果。在此应用程序中，我们请求支持 9名博士前和3名博士后学员继续我们非常成功和长期的培训 程序. 50名教职员工加入CRTP，提供包括实验室研究， 正式课程工作，计划活动，接触癌症的临床/转化方面，编程 专业发展和社区拓展机会。这些组件中的每一个都是 通过与UVA癌症中心的密切互动，为学员提供了独特的机会， 他们自己在基础癌症研究方面的经验，以及对改善癌症诊断和治疗的需求 在乎CRTP在其近39年的历史中取得了很大的成功，培训了数百名 癌症研究的年轻科学家，他们现在在学术界，工业界和教育界都有成功的职业生涯。 随着我们进入下一个资助期，我们挑战自己，以满足不断变化的癌症景观 研究通过（1）提供丰富和实质性的研究培训，使受训者接触到广泛的 现代癌症研究的深度;（2）重振我们的课程设置，并与我们的创新 教学模式;和（3）吸收我们的临床同事到培训计划的每一个组成部分。 我们教授的技能最终将有助于培养新一代的癌症研究人员，他们具有 对癌症生物学现状的赞赏，对将成为 在他们的一生中完成，以及追求研究事业的工具，这将有助于NCI的目标 “加快科学发现的速度，减轻癌症的负担”。

ABSTRACT The Cancer Research Training Program (CRTP) at the University of Virginia brings together faculty and trainees with a common interest in cancer biology to participate in an integrated program of cancer research and discovery. The overall objective of the CRTP is to develop a generation of cancer researchers who are facile with the newest techniques in cancer research; have a broad-based knowledge of cancer genomics and molecular drivers of cancer; and appreciate the tumor cell extrinsic, microenvironmental and immunological interactions that contribute to tumor growth and metastasis. In addition, our training program aims to develop trainees who are adept in partnering with basic scientists, translational researchers, clinical trialists, and physicians to promote discovery and improved outcomes in cancer care. In this application, we request support of 9 predoctoral and 3 postdoctoral trainees for continuation of our highly successful and long-standing training program. Fifty faculty members join the CRTP to provide a training program consisting of laboratory research, formal course work, programmatic activities, exposure to clinical/translational aspects of cancer, programming in professional development, and community outreach opportunities. Each of these components is facilitated by close interactions with the UVA Cancer Center, which provides unique opportunities for trainees to integrate their own experiences in basic cancer research with the need for improved diagnosis and treatments in cancer care. The CRTP has experienced much success over its almost 39-year history, having trained hundreds of young scientists in cancer research who now have successful careers in academia, industry, and education. As we move into the next funding period, we challenge ourselves to meet the changing landscape of cancer research by (1) offering rich and substantive research training that exposes the trainees to both the breadth and depth of modern cancer research; (2) reinvigorating our course offerings and being creative with our teaching modalities; and (3) assimilating our clinical colleagues into every component of the training program. The skills that we teach will ultimately help create a new generation of cancer researchers who have an appreciation for the current state of cancer biology, a vision for the extraordinary advances that will be accomplished in their lifetimes, and the tools to pursue research careers that will contribute to the NCI's goals of “accelerating the rate of scientific discovery and reducing the burden of cancer.”