Research Training in Systems Skin Biology

项目摘要/摘要 这个名为系统皮肤生物学研究培训的新T32应用程序是前后结合的 博士培训计划(MPIs Kim和Millar Co-PDs)。这一提议的理由是，伊坎学派 西奈山医学(ISMMS)在皮肤科、皮肤免疫学和皮肤科取得了成功 生物学，以便它可以利用其他机构的优势(例如，神经科学、转化医学、 等)建立系统皮肤生物学的跨学科培训计划。中心假设是这样的 交叉科学对于培养像这样的单一器官系统中的未来科学家至关重要 皮肤。最后，我们在以一种正式的方式培训内科科学家的能力方面存在一个重大差距，这就是 T32将提供一个成功做到这一点的平台。该计划的总体目标是吸引和培训 有才华的MD/博士和博士后学生和博士后超过2年的时间，为成功的，独立的职业生涯 与人类疾病相关的系统皮肤生物学。我们拥有一支多元化的、资金充足的教职员工队伍，对以下领域有广泛的兴趣 系统皮肤生物学免疫学和强大的博士前和博士后实习生人才库，包括 在科学(UIS)少数群体中代表性不足的人数。该计划旨在通过以下方式提供培训 个人导师在与人类疾病相关的系统皮肤生物学的各个方面进行研究。这个 该计划得到了强有力的监督和管理结构的支持，在系统方面进行了重要的教学培训 皮肤生物学，科学写作和职业发展，并包含新增加的最先进的评估 有明确的目标和成功基准的方法，以优化独立发展 该领域的学术研究人员。该计划的长期目标是培养1名医学博士或博士科学家 每两年进行一次皮肤病/皮肤生物学研究，他们通过K或 R机制。

PROJECT SUMMARY/ABSTRACT This new T32 application entitled Research Training in Systems Skin Biology is a combined pre- and post- doctoral training program (MPIs Kim and Millar Co-PDs). The rationale for this proposal is that Icahn School of Medicine at Mount Sinai (ISMMS) has a track record of success in dermatology, skin immunology, and epithelial biology such that it can leverage additional institutional strengths (e.g., neuroscience, translational medicine, etc.) to build an interdisciplinary training program in Systems Skin Biology. The central hypothesis is that such intersectional science is critically important for the training of future scientists within single organ systems like the skin. Finally, there is a major gap in our ability to train physician-scientist in a formalized manner which this T32 would provide a platform to do successfully. The overall objective of this program is to attract and train talented MD/PhD and PhD students and postdocs over 2 year periods, for successful, independent careers in Systems Skin Biology relevant to human disease. We have a diverse, well-funded faculty with broad interests in Systems Skin Biology in immunology and a strong pool of pre- and post-doc trainees that includes significant numbers of underrepresented in science (UiS) minorities. The program is designed to provide training by individual mentors performing research in all aspects of Systems Skin Biology relevant to human disease. The program is supported with strong oversight and administrative structure, significant didactic training in Systems Skin Biology, scientific writing and career development, and contains newly added state of the art evaluation approaches with defined goals and benchmarks for success so as to optimize the development of independent academic researchers in the field. The long-term goal of this program is to produce 1 MD/PhD or PhD scientist in investigative dermatology/skin biology research every 2 years who become independently funded via a K or R mechanism.