Underage alcohol use in youth with autism spectrum disorder

患有自闭症谱系障碍的青少年未成年人饮酒

• 批准号: 10165426
• 负责人: Emily F Rothman
• 金额: $ 20.27万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-15 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10165426
• 关键词: 20 year old; Address; Adolescent; Adult; Affect; Age; Agreement; Alcohol consumption; Alcohols; Award; Boston; Communication; Consequentialism; Data; Development; Diagnosis; Enrollment; Ensure; Equation; Evidence based intervention; Expectancy; Face; Factor Analysis; Feedback; Female; Frequencies; Future; Gender; Goals; Grant; Individual; Intellectual functioning disability; Intervention; Interview; Knowledge; Measures; Mediating; Medical center; Methods; Modeling; Motivation; Observational Study; Outcome; Parents; Participant; Patient Recruitments; Pattern; Perception; Population; Prevention program; Prevention strategy; Provider; Psychometrics; Qualitative Methods; Research; Risk; Sampling; Scheme; Self Efficacy; Services; Structure; Substance Use Disorder; Surveys; Target Populations; Techniques; Testing; Time; Validity and Reliability; Youth; adolescent with autism spectrum disorder; alcohol abstinence; alcohol expectancy; alcohol intervention; alcohol risk; alcohol use disorder; autism spectrum disorder; autistic children; cost effective; data format; design; drinking; experience; improved; individuals with autism spectrum disorder; informant; interest; male; parental monitoring; peer; prevent; preventive intervention; programs; psychosocial; public health priorities; recruit; risk perception; service providers; substance use; theories; therapy development; underage drinking

Project Summary There are now approximately 450,000 youth with autism spectrum disorder (ASD) between the ages of 16-24 in the U.S., and 50,000 more turning 18 each year. The field is bracing for a surge in demand for services. Underage alcohol use is a priority public health problem and too little is known about underage alcohol use by youth with ASD. ASD may be protective against alcohol use in individuals with intellectual disability, but 44% of youth with ASD have average or high IQ, and some evidence suggests that these ASD youth may be at increased risk for alcohol use disorder as compared to neurotypical counterparts. Information about underage alcohol use in youth with ASD, and ultimately effective prevention strategies, are needed. The proposed research will achieve two specific aims. Aim 1 is to explore, using qualitative methods, underage alcohol use and non-use by youth with ASD and without ID, ages 16-20 years old. Half of these youth will have used alcohol in the past six months and half will not (N=40). A targeted enrollment scheme will ensure that research participants include males and females. Aim 1 interviews will explore topics that include motivations to use alcohol or abstain, alcohol expectancies, refusal self-efficacy, parental communication about alcohol, peer use norms, alcohol rule-following, and perception of risks; and in those with recent alcohol use, types of alcohol consumed, how procured, where it occurred, when, with whom and in what context, perceived effects, and consequences. Aim 1 interview participants will also give feedback on a draft survey, comprising multiple measures of alcohol-related constructs, in order to improve its face validity prior to implementation in Aim 2. Aim 2 will use the refined survey to quantitatively investigate underage alcohol use in a sample of ASD vs. demographically-matched neurotypical comparison subjects (N=190). Half will have used alcohol in the past six months, and half will have abstained. Psychometrics will be assessed including factor structure and internal reliability of scales. Next, structural equation techniques will be used to evaluate relationships of alcohol- related variables with alcohol use among neurotypical vs. ASD youth in order to test hypotheses and inform theory development. In addition to assessing relationships between variables. For Aim 2, a targeted enrollment scheme to ensure that research participants include males and females will also be used. Overall, a strength of the project is its Advisory Board, comprising youth with ASD, parents of youth with ASD, and service providers. For recruitment of participants with ASD, the research team will partner with a leading national non-profit that serves the population formerly referred to as having Asperger’s, or referred to as high functioning ASD, and the Boston Medical Center Autism Program. In the long-term, the ultimate goal of this line of research is generalizable knowledge about underage alcohol use in U.S. youth with ASD and the development of evidence-based interventions to prevent it.

项目摘要 目前约有45万16-24岁的青少年患有自闭症谱系障碍(ASD) 在美国，每年还有5万人年满18岁。该领域正准备迎接服务需求的激增。 未成年人饮酒是一个优先的公共卫生问题，人们对未成年人饮酒知之甚少 患有自闭症的年轻人。对于智力残疾的人来说，ASD可能对饮酒有保护作用，但44%的人 患有自闭症的年轻人智商一般或很高，一些证据表明，这些自闭症年轻人可能在 与神经典型患者相比，酒精使用障碍的风险增加。有关未成年人的信息 需要对患有自闭症的青少年使用酒精，并最终采取有效的预防策略。建议数 研究将实现两个具体目标。目标1是用定性方法探索未成年人饮酒情况。 16-20岁患有自闭症和无身份证的青少年不能使用。这些年轻人中有一半会使用 在过去的六个半月内不会饮酒(N=40)。有针对性的招生计划将确保研究 参与者包括男性和女性。Aim 1访谈将探讨包括使用动机在内的主题 饮酒或戒酒、饮酒期望、拒绝自我效能感、父母关于饮酒的沟通、同伴使用 规范、酒精规则遵守和风险认知；以及在最近饮酒的人中，酒精类型 消费，如何获得，在哪里发生，何时，与谁，在什么背景下，感知到的影响，以及 后果。AIM 1面试参与者还将对调查草稿提供反馈，该调查包括多个 在目标2中实施之前，对与酒精相关的结构进行衡量，以提高其表面有效性。 目标2将使用改进的调查来定量调查ASD与VS的未成年酒精使用情况。 人口统计学上匹配的神经典型对照受试者(N=190)。一半的人会在过去饮酒 六个月，一半的人会弃权。心理测量学将被评估，包括因素结构和内部 量表的可靠性。接下来，将使用结构方程技术来评估酒精与 神经典型青少年与自闭症青少年酒精使用的相关变量，以检验假设并提供信息 理论发展。除了评估变量之间的关系之外。对于目标2，目标招生 也将采用确保研究参与者包括男性和女性的计划。总体而言， 该项目是其咨询委员会，由患有自闭症的青少年、患有自闭症的青少年的父母和服务提供者组成。 为了招募患有自闭症的参与者，研究团队将与一家领先的全国性非营利性组织合作 服务于以前被称为阿斯伯格综合症或高功能自闭症的人群，以及 波士顿医疗中心自闭症项目。从长远来看，这一系列研究的最终目标是 关于美国青少年自闭症青少年饮酒的概括性知识及其发展 以循证为基础的干预措施来预防它。

项目成果

Reasons for alcohol use and non-use by underage U.S. autistic youth: A qualitative study.

• DOI: 10.1177/13623613221091319
• 发表时间: 2023-01
• 期刊: AUTISM
• 影响因子: 5.2
• 作者: Rothman, Emily F.;Holmes, Laura Graham;Brooks, Dani;Krauss, Shari;Caplan, Reid
• 通讯作者: Caplan, Reid